SCHEMBL27090232

SCHEMBL27090232

O=S(=O)(c1ccc(Oc2cccc(S)c2)cc1)c1ccc(Oc2cccc(S)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 6/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
TDP1 Q9NUW8 1/20 0.61
SMN1; SMN2 Q16637 4/20 0.54
SOS1 Q07889 2/20 0.46
ALDH1A1 P00352 3/20 0.42
PKM P14618 1/20 0.42
LMNA P02545 4/20 0.42
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
MMP3 P08254 3/20 0.41
MMP8 P22894 2/20 0.41
MMP13 P45452 2/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
MMP1 P03956 1/20 0.41
MEN1 O00255 1/20 0.41
MITF O75030 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27090272 0.84 ALDH1A1 (0.54) HTTL3MBTL1TDP1SMN1; SMN2ALDH1A1
SCHEMBL27090263 0.81 HTT (0.55) HTTL3MBTL1TDP1SMN1; SMN2SOS1
SCHEMBL8674035 0.81 ALDH1A1 (0.50) HTTL3MBTL1TDP1SMN1; SMN2ALDH1A1
SCHEMBL10964994 0.79 HTT (0.61) HTTL3MBTL1TDP1SMN1; SMN2SOS1
SCHEMBL8741357 0.79 HTT (0.93) HTTL3MBTL1TDP1SMN1; SMN2SOS1
SCHEMBL11293951 0.79 HTT (0.61) HTTL3MBTL1TDP1SMN1; SMN2SOS1
SCHEMBL7180147 0.79 HTT (0.61) HTTL3MBTL1TDP1SMN1; SMN2SOS1
SCHEMBL9779074 0.79 HTT (0.61) HTTL3MBTL1TDP1SMN1; SMN2SOS1
SCHEMBL10712862 0.79 HTT (0.61) HTTL3MBTL1TDP1SMN1; SMN2SOS1
SCHEMBL19829814 0.79 HTT (0.87) HTTL3MBTL1TDP1SMN1; SMN2SOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240052103-A1 POLYMER AND TRIAZINE COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240052103-A1 POLYMER AND TRIAZINE COMPOUND TERT, TERB1, MCM5 HTT 1164/4885L3MBTL1 4114/4885TDP1 2325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.