Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8827179 | 0.89 | HTT (0.46) | HTTSMN1; SMN2ALDH1A1PKML3MBTL1 | |
| SCHEMBL6006737 | 0.85 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1PKMLMNAMAPT | |
| SCHEMBL636314 | 0.85 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1PKMLMNAMAPT | |
| SCHEMBL27605729 | 0.83 | SMN1; SMN2 (0.48) | HTTSMN1; SMN2ALDH1A1TDP1LMNA | |
| SCHEMBL13898960 | 0.83 | SMN1; SMN2 (0.48) | HTTSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL27090232 | 0.81 | HTT (0.61) | HTTSMN1; SMN2ALDH1A1PKML3MBTL1 | |
| SCHEMBL15929631 | 0.80 | ALDH1A1 (0.47) | HTTSMN1; SMN2ALDH1A1TDP1MAPT | |
| SCHEMBL636168 | 0.80 | ALDH1A1 (0.47) | HTTSMN1; SMN2ALDH1A1TDP1MAPT | |
| SCHEMBL9294674 | 0.80 | ALDH1A1 (0.47) | HTTSMN1; SMN2ALDH1A1TDP1MAPT | |
| SCHEMBL6123058 | 0.79 | HTT (0.81) | HTTSMN1; SMN2ALDH1A1PKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240052103-A1 | POLYMER AND TRIAZINE COMPOUND | TOKYO OHKA KOGYO CO., LTD. (JP) | 2024-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240052103-A1 | POLYMER AND TRIAZINE COMPOUND | TERT, TERB1, MCM5 | HTT 1164/4885SMN1; SMN2 2703/4885ALDH1A1 1603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.