Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 5/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27092631 | 0.83 | ABCG2 (0.48) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 | |
| SCHEMBL27074420 | 0.82 | TNNI3K (0.46) | ALDH1A1KDM4EGAAHTTMAPT | |
| SCHEMBL27199815 | 0.82 | TNNI3K (0.45) | ALDH1A1KDM4EGAAHTTMAPT | |
| SCHEMBL27092627 | 0.81 | LATS1 (0.52) | MAPTCSNK2A2CSNK2BCSNK2A1SMN1; SMN2 | |
| SCHEMBL27092619 | 0.81 | EPHB4 (0.45) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 | |
| SCHEMBL27182132 | 0.80 | CSNK2A1 (0.53) | ALDH1A1KDM4EGAAHTTMAPT | |
| SCHEMBL31356298 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAAHTTMAPT | |
| SCHEMBL27092629 | 0.79 | PIM1 (0.58) | ALDH1A1CSNK2A2CSNK2BCSNK2A1PIM1 | |
| SCHEMBL27092625 | 0.79 | PIM1 (0.58) | KDM4EMAPTCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL27092623 | 0.79 | IDO1 (0.46) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12240851-B1 | Pyrido[3′,4′:4,5]pyrrolo[3,2-c]naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2025-03-04 | — | — | US | claimed |
| US-20250066362-A1 | PYRIDO[3',4':4,5]PYRROLO[3,2-C]NAPHTHYRIDINE COMPOUNDS AS CK2 INHIBITORS | King Faisal University (SA) | 2025-02-27 | — | — | US | claimed |
| US-11905289-B1 | Pyrido[3′,4′:4,5]pyrrolo[3,2-C]naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2024-02-20 | — | — | US | claimed |
| US-12240851-B1 | Pyrido[3′,4′:4,5]pyrrolo[3,2-c]naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2025-03-04 | — | — | US | disclosed |
| US-20250066362-A1 | PYRIDO[3',4':4,5]PYRROLO[3,2-C]NAPHTHYRIDINE COMPOUNDS AS CK2 INHIBITORS | King Faisal University (SA) | 2025-02-27 | — | — | US | disclosed |
| US-11905289-B1 | Pyrido[3′,4′:4,5]pyrrolo[3,2-C]naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2024-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066362-A1 | PYRIDO[3',4':4,5]PYRROLO[3,2-C]NAPHTHYRIDINE COMPOUNDS AS CK2 INHIBITORS | CKS2, CDK2, PNKP | ALDH1A1 4511/4885KDM4E 2222/4885GAA 1405/4885 |
| US-12240851-B1 | Pyrido[3′,4′:4,5]pyrrolo[3,2-c]naphthyridine compounds as CK2 inhibitors | CKS2, CDK2, PNKP | ALDH1A1 4513/4885KDM4E 2254/4885GAA 1375/4885 |
| US-11905289-B1 | Pyrido[3′,4′:4,5]pyrrolo[3,2-C]naphthyridine compounds as CK2 inhibitors | CKS2, CDK2, PNKP | ALDH1A1 4513/4885KDM4E 2254/4885GAA 1375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.