Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30998001 | 0.85 | MAPT (0.46) | ALDH1A1MAPTLMNASMN1; SMN2GPR174 | |
| SCHEMBL27094352 | 0.85 | MAPT (0.46) | ALDH1A1MAPTLMNASMN1; SMN2GPR174 | |
| SCHEMBL27094458 | 0.79 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL9261808 | 0.74 | KMT2A (0.47) | ALDH1A1MAPTLMNASMN1; SMN2GRM5 | |
| SCHEMBL27094393 | 0.73 | MAPT (0.40) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL30998006 | 0.73 | MAPT (0.40) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL21050774 | 0.71 | MAPT (0.38) | ABL1BCRALDH1A1MAPTLMNA | |
| SCHEMBL29889640 | 0.70 | ALDH1A1 (0.34) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL27094347 | 0.70 | ALDH1A1 (0.34) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL21136735 | 0.70 | KCNH2 (0.47) | ALDH1A1MAPTLMNASMN1; SMN2GPR174 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4322945-A2 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |