Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 5/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | KIF5B | P33176 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 5/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24668334 | 0.83 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CAPPRET | |
| SCHEMBL1488396 | 0.82 | APP (0.53) | ADRA2AADRA2BADRA2CAPPESR1 | |
| SCHEMBL5512117 | 0.78 | ESR1 (0.49) | ADRA2AADRA2BADRA2CAPPCYP3A4 | |
| SCHEMBL16280538 | 0.77 | ADRA2A (0.38) | ADRA2AADRA2BADRA2CRETKIF5B | |
| SCHEMBL21635491 | 0.77 | CYP3A4 (0.63) | ADRA2AADRA2BADRA2CRETKIF5B | |
| SCHEMBL5795933 | 0.76 | IDO1 (0.45) | APPCYP3A4TSHRRECQLESR1 | |
| SCHEMBL1547786 | 0.76 | CA3 (0.42) | TSHRMEN1MAPTRAB9AKMT2A | |
| SCHEMBL30963343 | 0.76 | IDO1 (0.45) | APPCYP3A4TSHRRECQLESR1 | |
| SCHEMBL21678086 | 0.75 | ALDH1A1 (0.48) | CYP3A4TSHRKDM4EMEN1MAPT | |
| SCHEMBL8504632 | 0.74 | CYP3A4 (0.61) | RETKIF5BKDRCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445969-B1 | NOVEL FLUORINATED RHODAMINES AS PHOTOSTABLE FLUORESCENT DYES FOR LABELLING AND IMAGING TECHNIQUES | MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V (DE) | 2014-08-27 | — | — | EP | disclosed |
| US-8735444-B2 | Fluorinated rhodamines as photostable fluorescent dyes for labelling and imaging techniques | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2014-05-27 | — | — | US | disclosed |
| US-20120135459-A1 | NOVEL FLUORINATED RHODAMINES AS PHOTOSTABLE FLUORESCENT DYES FOR LABELLING AND IMAGING TECHNIQUES | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2012-05-31 | — | — | US | disclosed |
| EP-2445969-A1 | NOVEL FLUORINATED RHODAMINES AS PHOTOSTABLE FLUORESCENT DYES FOR LABELLING AND IMAGING TECHNIQUES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010149190-A1 | NOVEL FLUORINATED RHODAMINES AS PHOTOSTABLE FLUORESCENT DYES FOR LABELLING AND IMAGING TECHNIQUES | MAX-PLANCK-GESELLSCHAFT ZUR (DE) | 2010-12-29 | — | — | WO | disclosed |
| CN-100478364-C | Ethylene polymer and molded article obtained therefrom | MITSUI CHEMICALS INC (JP) | 2009-04-15 | — | — | CN | disclosed |
| US-7208559-B2 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2007-04-24 | — | — | US | disclosed |
| US-20060135712-A1 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2006-06-22 | — | — | US | disclosed |
| CN-1732189-A | Ethylene polymer and molded article obtained therefrom | MITSUI CHEMICALS INC (JP) | 2006-02-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135459-A1 | NOVEL FLUORINATED RHODAMINES AS PHOTOSTABLE FLUORESCENT DYES FOR LABELLING AND IMAGING TECHNIQUES | SNRPD1, SRSF6, DRD1 | ADRA2A 2195/4885ADRA2B 1244/4885ADRA2C 1717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.