Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30746295 | 1.00 | GPR183 (0.35) | GPR183IDO1HRH3GPR119KDM4E | |
| SCHEMBL27095388 | 0.81 | MTOR (0.37) | GPR183HRH3GPR119USP30SCD5 | |
| SCHEMBL30746089 | 0.81 | MTOR (0.37) | GPR183HRH3GPR119USP30SCD5 | |
| SCHEMBL31024668 | 0.72 | EED (0.36) | GPR183IDO1HRH3GPR119KDM4E | |
| SCHEMBL31024662 | 0.72 | EED (0.36) | GPR183IDO1HRH3GPR119KDM4E | |
| SCHEMBL25345030 | 0.72 | EED (0.36) | GPR183IDO1HRH3GPR119KDM4E | |
| SCHEMBL30746323 | 0.71 | GPR119 (0.38) | GPR183IDO1HRH3GPR119KDM4E | |
| SCHEMBL27095258 | 0.71 | GPR119 (0.38) | GPR183IDO1HRH3GPR119KDM4E | |
| SCHEMBL27095389 | 0.69 | GPR183 (0.38) | GPR183IDO1HRH3GPR119PDK2 | |
| SCHEMBL31024669 | 0.68 | GPR119 (0.40) | GPR183IDO1HRH3GPR119KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240059704-A1 | Cereblon Ligands and Uses Thereof | ONCOPIA THERAPEUTICS, INC. D/B/A/ PROTEOVANT THERAPEUTICS, INC. | 2024-02-22 | — | — | US | disclosed |
| WO-2024015412-A1 | TETRAHYDRONAPHTHALENE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240059704-A1 | Cereblon Ligands and Uses Thereof | CRBN, CDR2, CHLSN | GPR183 761/4885IDO1 3182/4885HRH3 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.