Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.36 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31024717 | 0.94 | GPR119 (0.43) | GPR119GPR183IDO1PKMHRH3 | |
| SCHEMBL31024681 | 0.88 | PKM (0.42) | GPR119GPR183IDO1PKMHRH3 | |
| SCHEMBL31024719 | 0.88 | PKM (0.42) | GPR119GPR183IDO1PKMHRH3 | |
| SCHEMBL25345030 | 0.85 | EED (0.36) | GPR119GPR183IDO1PKMHRH3 | |
| SCHEMBL31024662 | 0.85 | EED (0.36) | GPR119GPR183IDO1PKMHRH3 | |
| SCHEMBL31024668 | 0.85 | EED (0.36) | GPR119GPR183IDO1PKMHRH3 | |
| SCHEMBL31738784 | 0.84 | GPR119 (0.42) | GPR119GPR183IDO1PKMHRH3 | |
| SCHEMBL25342331 | 0.83 | HDAC3 (0.46) | GPR119PKMHDAC2KDM4EALDH1A1 | |
| SCHEMBL25344960 | 0.82 | IDO1 (0.42) | GPR119GPR183IDO1PKMHRH3 | |
| SCHEMBL31024670 | 0.81 | GPR119 (0.46) | GPR119IDO1PKMHRH3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026283-A1 | COMPOUND FOR SELECTIVELY DEGRADING SMARCA2/4 AND USE THEREOF | 甘李药业股份有限公司 | 2025-02-06 | — | — | WO | disclosed |
| WO-2024156294-A1 | ESTROGEN RECEPTOR PROTEOLYSIS TARGETING CHIMERA COMPOUND AND USE THEREOF | 甘李药业股份有限公司 | 2024-08-02 | — | — | WO | disclosed |