SCHEMBL27097201

SCHEMBL27097201

C=C(N)NC1CCN(C(C)C)CC1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
HRH3 Q9Y5N1 6/20 0.42
CYP2D6 P10635 2/20 0.42
PARP1 P09874 1/20 0.39
MAPT P10636 1/20 0.38
ACKR3 P25106 2/20 0.36
KDM1A O60341 1/20 0.36
CYP3A4 P08684 1/20 0.36
HTR4 Q13639 1/20 0.36
WHR1 P49842 1/20 0.35
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
F10 P00742 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18087093 0.82 ALDH1A1 (0.46) ALDH1A1HRH3CYP2D6PARP1MAPT
SCHEMBL16158913 0.81 ALDH1A1 (0.45) ALDH1A1HRH3CYP2D6PARP1MAPT
SCHEMBL12537397 0.81 ALDH1A1 (0.45) ALDH1A1HRH3CYP2D6PARP1MAPT
SCHEMBL2106067 0.81 ALDH1A1 (0.53) ALDH1A1HRH3CYP2D6PARP1MAPT
Hydrochloric Acid SCHEMBL9956472 0.79 ALDH1A1 (0.44) ALDH1A1HRH3CYP2D6PARP1MAPT
SCHEMBL16904624 0.79 ALDH1A1 (0.44) ALDH1A1HRH3CYP2D6PARP1MAPT
SCHEMBL2948497 0.74 ALDH1A1 (0.58) ALDH1A1HRH3CYP2D6PARP1MAPT
SCHEMBL12026487 0.74 ALDH1A1 (0.54) ALDH1A1HRH3CYP2D6PARP1MAPT
SCHEMBL12530176 0.74 ALDH1A1 (0.46) ALDH1A1HRH3CYP2D6PARP1MAPT
SCHEMBL13300924 0.74 ALDH1A1 (0.50) ALDH1A1HRH3CYP2D6PARP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11911403-B2 Antisense-induced exon exclusion in type VII collagen SAREPTA THERAPEUTICS, INC. (US) 2024-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11911403-B2 Antisense-induced exon exclusion in type VII collagen COL2A1, COL14A1, COL1A1 ALDH1A1 4425/4885HRH3 4497/4885CYP2D6 3462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.