SCHEMBL2709894

SCHEMBL2709894

Nc1ccc(Oc2cccc(Oc3ccc(N)c(C45CC6CC(CC(C6)C4)C5)c3)c2)cc1C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MITF O75030 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
GFER P55789 1/20 0.43
NLRP1 Q9C000 1/20 0.43
NOD2 Q9HC29 1/20 0.43
NR4A1 P22736 1/20 0.39
EPHX2 P34913 2/20 0.38
LMNA P02545 2/20 0.38
PTPN11 Q06124 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
MAOB P27338 1/20 0.35
FURIN P09958 2/20 0.35
F2 P00734 1/20 0.35
F10 P00742 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2709102 0.83 NCOA1 (0.40) ALDH1A1MEN1KMT2AGAAMAPT
SCHEMBL2709061 0.80 MEN1 (0.38) ALDH1A1MEN1KMT2ASMN1; SMN2MITF
SCHEMBL2706916 0.77 EPHX2 (0.45) ALDH1A1MEN1KMT2ASMN1; SMN2MAPT
SCHEMBL2709890 0.77 ALDH1A1 (0.42) ALDH1A1MEN1KMT2ASMN1; SMN2MITF
SCHEMBL2708150 0.76 MEN1 (0.37) ALDH1A1MEN1KMT2ASMN1; SMN2MITF
SCHEMBL16047327 0.75 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ASMN1; SMN2MITF
SCHEMBL2709058 0.74 FURIN (0.36) ALDH1A1MEN1KMT2ASMN1; SMN2MITF
SCHEMBL27829414 0.72 MEN1 (0.46) ALDH1A1MEN1KMT2ASMN1; SMN2GAA
SCHEMBL2707709 0.71 MEN1 (0.38) ALDH1A1MEN1KMT2ASMN1; SMN2GAA
SCHEMBL25125099 0.71 ALDH1A1 (0.48) ALDH1A1MEN1KMT2ASMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2000510-B1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM SUMITOMO BAKELITE CO (JP) 2012-05-02 EP disclosed
US-7863347-B2 Resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2011-01-04 US disclosed
US-7652125-B2 Resin composition, polyimide resin composition, polybenzoxazole resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2010-01-26 US disclosed
US-20090118431-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE COMPANY, LTD (JP) 2009-05-07 US disclosed
EP-2000510-A1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM Sumitomo Bakelite Company, Ltd. (JP) 2008-12-10 EP disclosed
US-20080255335-A1 Resin Composition, Polyimide Resin Composition, Polybenzoxazole Resin Composition, Varnish, Resin Film and Semiconductor Device Using the Same SUMITOMO BAKELITE COMPANY LTD. (JP) 2008-10-16 US disclosed
EP-1813637-A1 RESIN COMPOSITION, POLYIMIDE RESIN COMPOSITION, POLY- BENZOXAZOLE RESIN COMPOSITION, VARNISHES, RESIN FILMS AND SEMICONDUCTOR DEVICES MADE BY USING THE SAME Sumitomo Bakelite Company, Limited (JP) 2007-08-01 EP disclosed