SCHEMBL2709972

SCHEMBL2709972

COc1cc(F)c(-c2c3cc(F)c(F)cc3c(-c3c(F)c(F)cc(F)c3F)c3c(F)cccc23)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
MIF P14174 1/20 0.32
NFE2L2 Q16236 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30
CDK2 P24941 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2725925 0.93 NFE2L2 (0.34) ALDH1A1MIFNFE2L2TAAR1CDK2
SCHEMBL2725617 0.93 ALDH1A1 (0.33) ALDH1A1MIFNFE2L2TAAR1CDK2
SCHEMBL2726766 0.90 ALDH1A1 (0.33) ALDH1A1MIFNFE2L2TAAR1CDK2
SCHEMBL2942677 0.90 TSHR (0.32) ALDH1A1MIF
SCHEMBL2711131 0.89 ALDH1A1 (0.33) ALDH1A1MIFNFE2L2TAAR1CDK2
SCHEMBL2712328 0.88 ANPEP (0.32) ALDH1A1MIFNFE2L2
SCHEMBL2943796 0.87 TAAR1 (0.34) ALDH1A1NFE2L2TAAR1
SCHEMBL12086104 0.86 GRM8 (0.32)
SCHEMBL2712158 0.86 GRM8 (0.32)
SCHEMBL2709778 0.86 NFE2L2 (0.35) ALDH1A1MIFNFE2L2TAAR1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
EP-2445987-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS Cyalume Technologies, Inc (US) 2012-05-02 EP disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
WO-2010151654-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECHNOLOGIES, INC. (US) 2010-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYP2F1, FLAD1, AFF1 ALDH1A1 34/4885MIF 3740/4885NFE2L2 346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.