SCHEMBL2943796

SCHEMBL2943796

COc1cc(F)c(-c2c3ccccc3c(-c3c(F)c(F)cc(F)c3F)c3cc(F)c(F)cc23)c(F)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.34
L3MBTL1 Q9Y468 3/20 0.33
CYP1A2 P05177 3/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33
ALDH1A1 P00352 6/20 0.32
MAPT P10636 5/20 0.32
KDM4E B2RXH2 5/20 0.32
MAOA P21397 2/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
GRM2 Q14416 1/20 0.32
KDM1A O60341 1/20 0.32
MAOB P27338 1/20 0.32
GAA P10253 1/20 0.32
EPAS1 Q99814 1/20 0.32
LMNA P02545 1/20 0.32
MEN1 O00255 2/20 0.32
HPGD P15428 2/20 0.32
KMT2A Q03164 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2712953 0.95 TAAR1 (0.37) TAAR1L3MBTL1CYP1A2CYP1A1CYP1B1
SCHEMBL2712306 0.92 TAAR1 (0.35) TAAR1L3MBTL1CYP1A2CYP1A1CYP1B1
SCHEMBL2711581 0.92 TAAR1 (0.39) TAAR1L3MBTL1CYP1A2CYP1A1CYP1B1
SCHEMBL2710435 0.90 MAOB (0.34) L3MBTL1ALDH1A1MAPTKDM4EMAOA
SCHEMBL2710509 0.88 L3MBTL1 (0.36) TAAR1L3MBTL1CYP1A2CYP1A1CYP1B1
SCHEMBL2943764 0.88 KDM4E (0.36) TAAR1L3MBTL1CYP1A2CYP1A1CYP1B1
SCHEMBL2710519 0.88 MAOB (0.35) TAAR1CYP1A2CYP1A1CYP1B1ALDH1A1
SCHEMBL2709972 0.87 ALDH1A1 (0.33) TAAR1ALDH1A1NFE2L2
SCHEMBL2727079 0.87 TAAR1 (0.38) TAAR1L3MBTL1CYP1A2CYP1A1CYP1B1
SCHEMBL2712308 0.87 TAAR1 (0.42) TAAR1L3MBTL1CYP1A2CYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYP2F1, FLAD1, AFF1 TAAR1 1993/4885L3MBTL1 2477/4885CYP1A2 22/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.