SCHEMBL2710001

SCHEMBL2710001

N#CC=CC(C=Cc1ccccc1)=Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.42
LMNA P02545 4/20 0.42
HDAC3 O15379 2/20 0.42
HDAC4 P56524 2/20 0.42
HDAC1 Q13547 2/20 0.42
HDAC2 Q92769 2/20 0.42
HDAC8 Q9BY41 2/20 0.42
HDAC6 Q9UBN7 2/20 0.42
PLIN1 O60240 2/20 0.42
RECQL P46063 2/20 0.42
PLIN5 Q00G26 2/20 0.42
ABHD5 Q8WTS1 2/20 0.42
ALDH1A1 P00352 2/20 0.42
TNKS O95271 1/20 0.42
HCAR2 Q8TDS4 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
TNKS2 Q9H2K2 1/20 0.42
HDAC9 Q9UKV0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6061065 0.93 MCL1 (0.43) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL123981 0.86 LMNA (0.42) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL29670874 0.84 MAPT (0.56) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL11113773 0.83 RAB9A (0.35) MAPTLMNAALDH1A1CYP1A2CYP2D6
SCHEMBL307061 0.83 HCAR2 (0.44) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL9960390 0.82 MCL1 (0.39) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL9722970 0.82 GLA (0.40) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL8089911 0.81 HDAC3 (0.52) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL116598 0.81 LMNA (0.39) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL258376 0.81 MCL1 (0.36) MAPTLMNAPLIN1PLIN5ABHD5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1386592-A2 Resealable coupling device E.R. SQUIBB & SONS, INC. (US) 2004-02-04 EP claimed
EP-0954342-B1 OSTOMY APPLIANCE AND WOUND DRAINAGE DEVICE SQUIBB & SONS INC (US) 2003-10-15 EP claimed
US-6387082-B1 Ostomy appliance and wound drainage device and method of using the same E. R. SQUIBB & SONS, INC. 2002-05-14 US claimed
EP-0954342-A4 1999-11-17 EP claimed
EP-0954342-A1 OSTOMY APPLIANCE AND WOUND DRAINAGE DEVICE E.R. SQUIBB & SONS, INC. (US) 1999-11-10 EP claimed
US-5951533-A Ostomy appliance and wound drainage device and method of using the same E.R. SQUIBB & SONS, INC (US) 1999-09-14 US claimed
WO-1996003167-A1 OSTOMY APPLIANCE AND WOUND DRAINAGE DEVICE E.R. SQUIBB & SONS, INC. (US) 1996-02-08 WO claimed
CN-112662121-B ABS resin material with low butadiene monomer content and preparation method thereof 上海普利特复合材料股份有限公司 2023-09-08 CN disclosed
CN-111094381-B Process for producing thermoplastic polyoxazolidone polymers 科思创德国股份有限公司 2022-03-22 CN disclosed
CN-112662121-A ABS resin material with low butadiene monomer content and preparation method thereof 上海普利特复合材料股份有限公司 2021-04-16 CN disclosed
CN-112372863-A Supporting plate for silicon ingot slicing and manufacturing method thereof 江西中昱新材料科技有限公司 2021-02-19 CN disclosed
CN-102458497-B Catheter balloon coated with shellac and paclitaxel 生物传感器欧洲股份公司 2020-11-24 CN disclosed
CN-111655482-A Multilayer polymer structure 阿科玛法国公司 2020-09-11 CN disclosed
EP-0610016-B2 1-Cyclohexyl-1-methylethylperoxy carbonates, method for production thereof, and uses therefor NOF CORP (JP) 1999-10-20 EP disclosed
US-5446191-A Polymerization initiator for vinyl monomer, curing agent for unsaturated polyester NOF CORPORATION (JP) 1995-08-29 US disclosed
EP-0610016-A1 1-Cyclohexyl-1-methylethylperoxy carbonates, method for production thereof, and uses therefor NOF CORPORATION (JP) 1994-08-10 EP disclosed
EP-0488119-A2 Mouldable thermoplastic resin composition NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-06-03 EP disclosed
US-5080968-A Molding materials THE B. F. GOODRICH COMPANY (US) 1992-01-14 US disclosed
EP-0154097-A1 Modified polycarbonate compositions GENERAL ELECTRIC COMPANY (US) 1985-09-11 EP disclosed
US-4503183-A ENGINEERING THEMOPLASTICS Barancik, Martin B. (US) 1985-03-05 US disclosed