SCHEMBL116598

SCHEMBL116598

C=CC=C(C=CC#N)C=Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.39
MAPT P10636 3/20 0.39
ALDH1A1 P00352 3/20 0.39
HDAC3 O15379 2/20 0.39
HDAC4 P56524 2/20 0.39
HDAC1 Q13547 2/20 0.39
HDAC2 Q92769 2/20 0.39
HDAC8 Q9BY41 2/20 0.39
HDAC6 Q9UBN7 2/20 0.39
PLIN1 O60240 2/20 0.39
RECQL P46063 2/20 0.39
PLIN5 Q00G26 2/20 0.39
ABHD5 Q8WTS1 2/20 0.39
TNKS O95271 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
HDAC9 Q9UKV0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7651130 0.86 MAPT (0.50) LMNAMAPTALDH1A1HDAC3HDAC4
Serine SCHEMBL6128183 0.84 GRIK1 (0.40) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL5054667 0.84 GLA (0.38) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL2710001 0.81 MAPT (0.42) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL123981 0.81 LMNA (0.42) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL6432104 0.80 LMNA (0.36) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL26079487 0.80 ALDH1A1 (0.44) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL1245521 0.80 ALDH1A1 (0.44) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL5069733 0.79 LMNA (0.38) LMNAMAPTALDH1A1HDAC3HDAC4
SCHEMBL19058802 0.79 MAPT (0.47) LMNAMAPTALDH1A1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1053 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3733399-B1 BLOCK COPOLYMER COMPOSITION, PREPREGS, AND LAMINATES MADE THEREFROM KRATON POLYMERS RES BV (NL) 2024-04-24 EP claimed
CN-111875916-B Block copolymer composition, prepreg, and laminate prepared therefrom 克拉通聚合物研究有限公司 2023-12-12 CN claimed
CN-112662121-B ABS resin material with low butadiene monomer content and preparation method thereof 上海普利特复合材料股份有限公司 2023-09-08 CN claimed
CN-116120678-A ABS resin for 3D printing and preparation method thereof 吉林化工学院 2023-05-16 CN claimed
CN-115433396-A Carbon composite material, high-reinforcement rubber material, and preparation method and application thereof 北京诺维新材科技有限公司 2022-12-06 CN claimed
CN-109575551-B Modified resin material for heat conduction and heat dissipation and preparation method and application thereof 中国石油化工股份有限公司 2021-12-28 CN claimed
US-11123459-B2 Hydrophobic active agent particle coatings and methods for treatment SURMODICS, INC. (US) 2021-09-21 US claimed
CN-112662121-A ABS resin material with low butadiene monomer content and preparation method thereof 上海普利特复合材料股份有限公司 2021-04-16 CN claimed
CN-109438866-B Carbon fiber/ABS composite material for 3D printing and preparation method thereof 吉林化工学院 2021-04-09 CN claimed
CN-111875916-A Block copolymer composition, prepreg, and laminate prepared therefrom 克拉通聚合物研究有限公司 2020-11-03 CN claimed
US-4804581-A CURED LAYERS OF POLYEPOXIDE-DIENE POLYMER COPOLYMER AND A CARBOXYL-CONTAINING POLYMER OR COMPOUND; POWDER COATING; AUTOMOBILE PROTECTIVE COATINGS PPG INDUSTRIES, INC. (US) 1989-02-14 US claimed
EP-0292771-A2 Chip resistant coatings PPG INDUSTRIES, INC. (US) 1988-11-30 EP claimed
EP-0232592-A1 Dispersions of fibres in rubber POLYSAR LIMITED (CA) 1987-08-19 EP claimed
US-4659754-A PRETREATMENT WITH PLASTICIZER POLYSAR LIMITED (CA) 1987-04-21 US claimed
US-4645803-A AROMATIC ETHER-SULFONE POLYAMINE CURING AGENTS; REINFORCING FIBERS; AIRCRAFT AMERICAN CYANAMID COMPANY (US) 1987-02-24 US claimed
EP-0035661-A2 Continuous process for the removal of monomers from polymeric emulsions Montedison S.p.A. (IT) 1981-09-16 EP claimed
US-4252911-A Mass polymerization process for ABS polyblends MONSANTO COMPANY (US) 1981-02-24 US claimed
US-3962156-A ALDEHYDE-PHENOL-POLYAMINE REACTION PRODUCT ROHM AND HAAS COMPANY (US) 1976-06-08 US claimed
US-3961987-A ELECTRO-CATALYST AND PROCESS OF MANUFACTURE SIEMENS AKTIENGESELLSCHAFT (DT) 1976-06-08 US claimed
US-3931356-A POLYMERIZATION MONSANTO COMPANY (US) 1976-01-06 US claimed