Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 17/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22078769 | 0.85 | LMNA (0.40) | OGAUSP7SMN1; SMN2 | |
| SCHEMBL22078761 | 0.83 | OGA (0.56) | OGA | |
| SCHEMBL26374189 | 0.81 | OGA (0.45) | OGASMN1; SMN2 | |
| SCHEMBL20684924 | 0.72 | HRH3 (0.36) | USP7 | |
| Hydrochloric Acid SCHEMBL29232460 | 0.68 | USP7 (0.36) | USP7SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29232267 | 0.68 | USP7 (0.36) | USP7SMN1; SMN2 | |
| SCHEMBL23240245 | 0.68 | FDPS (0.51) | OGASMN1; SMN2 | |
| SCHEMBL21370037 | 0.66 | OGA (0.44) | OGASMN1; SMN2 | |
| SCHEMBL22432786 | 0.66 | OGA (0.62) | OGA | |
| SCHEMBL21370045 | 0.65 | ALDH1A1 (0.47) | OGASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4327814-A2 | MORPHOLINYL, PIPERAZINYL, OXAZEPANYL AND DIAZEPANYL O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | Biogen MA Inc. (US) | 2024-02-28 | — | — | EP | disclosed |