SCHEMBL2710076

SCHEMBL2710076

CC12CC3CC(C)(C1)CC(c1ccc(Oc4ccc(C#Cc5cccc(C(=O)O)c5C(=O)O)cc4)cc1)(C3)C2

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.36
EPAS1 Q99814 2/20 0.36
PGR P06401 7/20 0.32
EPHX2 P34913 1/20 0.32
FFAR1 O14842 1/20 0.32
HAO1 Q9UJM8 4/20 0.31
CYP26A1 O43174 1/20 0.30
CYP3A4 P08684 1/20 0.30
RARA P10276 1/20 0.30
RARB P10826 1/20 0.30
RARG P13631 1/20 0.30
CRABP2 P29373 1/20 0.30
MEN1 O00255 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2706663 0.94 PGR (0.35) HIF1AEPAS1PGREPHX2FFAR1
SCHEMBL2709552 0.86 HIF1A (0.48) HIF1AEPAS1EPHX2MEN1RAB9A
SCHEMBL3179396 0.83 RARB (0.37) HIF1AEPAS1PGREPHX2HAO1
SCHEMBL2710041 0.83 RARB (0.39) HIF1AEPAS1PGRCYP26A1CYP3A4
SCHEMBL2708265 0.83 RARB (0.39) HIF1AEPAS1PGRCYP26A1CYP3A4
SCHEMBL2709090 0.80 RARB (0.40) HIF1AEPAS1PGREPHX2CYP26A1
SCHEMBL2709267 0.79 HIF1A (0.46) HIF1AEPAS1PGREPHX2MEN1
SCHEMBL2707916 0.78 FFAR1 (0.36) HIF1AEPAS1EPHX2FFAR1HAO1
SCHEMBL2710078 0.77 FFAR1 (0.32) FFAR1HAO1
SCHEMBL2709689 0.76 RARB (0.39) PGREPHX2CYP26A1CYP3A4RARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2000510-B1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM SUMITOMO BAKELITE CO (JP) 2012-05-02 EP disclosed
US-7863347-B2 Resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2011-01-04 US disclosed
US-7652125-B2 Resin composition, polyimide resin composition, polybenzoxazole resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2010-01-26 US disclosed
US-20090118431-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE COMPANY, LTD (JP) 2009-05-07 US disclosed
EP-2000510-A1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM Sumitomo Bakelite Company, Ltd. (JP) 2008-12-10 EP disclosed
US-20080255335-A1 Resin Composition, Polyimide Resin Composition, Polybenzoxazole Resin Composition, Varnish, Resin Film and Semiconductor Device Using the Same SUMITOMO BAKELITE COMPANY LTD. (JP) 2008-10-16 US disclosed
EP-1813637-A1 RESIN COMPOSITION, POLYIMIDE RESIN COMPOSITION, POLY- BENZOXAZOLE RESIN COMPOSITION, VARNISHES, RESIN FILMS AND SEMICONDUCTOR DEVICES MADE BY USING THE SAME Sumitomo Bakelite Company, Limited (JP) 2007-08-01 EP disclosed