SCHEMBL2710099

SCHEMBL2710099

O=C(C(=O)c1c(O)c(O)c(O)c(O)c1C(=O)c1ccccc1)c1c(O)c(O)c(O)c(O)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
CES2 O00748 5/20 0.48
CES1 P23141 4/20 0.48
ATM Q13315 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SRD5A2 P31213 1/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
LMNA P02545 2/20 0.45
MAPT P10636 2/20 0.45
RAB9A P51151 1/20 0.45
HSD17B10 Q99714 1/20 0.44
AKR1C3 P42330 1/20 0.43
BCL2 P10415 1/20 0.43
MCL1 Q07820 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
DAO P14920 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1064484 0.86 ALDH1A1 (0.65) ALDH1A1CES2CES1ATMTDP1
SCHEMBL27789267 0.82 ALDH1A1 (0.59) ALDH1A1CES2CES1ATMTDP1
SCHEMBL28678655 0.79 ALDH1A1 (0.68) ALDH1A1CES2CES1ATMTDP1
SCHEMBL29213656 0.77 ALDH1A1 (0.52) ALDH1A1CES2CES1ATMTDP1
SCHEMBL6878151 0.76 LMNA (0.47) ALDH1A1ATMTDP1L3MBTL1SRD5A2
Benzophenone SCHEMBL6061130 0.72 ALDH1A1 (1.00) ALDH1A1CES2CES1ATMTDP1
Benzophenone SCHEMBL28491203 0.72 ALDH1A1 (1.00) ALDH1A1CES2CES1ATMTDP1
Benzophenone SCHEMBL30536983 0.72 ALDH1A1 (1.00) ALDH1A1CES2CES1ATMTDP1
Benzophenone SCHEMBL30537001 0.72 ALDH1A1 (1.00) ALDH1A1CES2CES1ATMTDP1
Benzophenone SCHEMBL1074283 0.72 ALDH1A1 (1.00) ALDH1A1CES2CES1ATMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130324595-A1 C-GLUCOSIDIC ELLAGITANNIN COMPOUNDS FOR USE FOR ALTERING THE SUPRAMOLECULAR ARRANGEMENT OF ACTIN AND FOR THE TREATMENT OF OSTEOPOROSIS, CANCER, BACTERIAL INFECTION AND VIRAL INFECTION INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2013-12-05 US disclosed
WO-2012113835-A1 C-GLUCOSIDIC ELLAGITANNIN COMPOUNDS FOR USE FOR ALTERING THE SUPRAMOLECULAR ARRANGEMENT OF ACTIN AND FOR THE TREATMENT OF OSTEOPOROSIS, CANCER, BACTERIAL INFECTION AND VIRAL INFECTION INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2012-08-30 WO disclosed
EP-1901735-B1 Polyphenol type compounds for the manufacture of a composition for preventing or treating diseases involving abnormal cell proliferation FLUOFARMA (FR) 2012-05-02 EP disclosed
EP-1901735-A2 POLYPHENOL TYPE COMPOUNDS, COMPOSITIONS CONTAINING SAME AND USE THEREOF FOR PREVENTING OR TREATING DISEASES INVOLVING ABNORMAL CELL PROLIFERATION Fluofarma (FR) 2008-03-26 EP disclosed
WO-2007003741-A2 POLYPHENOL TYPE COMPOUNDS, COMPOSITIONS CONTAINING SAME AND USE THEREOF FOR PREVENTING OR TREATING DISEASES INVOLVING ABNORMAL CELL PROLIFERATION FLUOFARMA (FR) 2007-01-11 WO disclosed