SCHEMBL2710141

SCHEMBL2710141

O=C(O)c1ccc(C#Cc2ccc(Oc3ccc(C45CC6CC(CC(C6)C4)C5)cc3)cc2)c(C(=O)O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 11/20 0.48
EPAS1 Q99814 6/20 0.48
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
SERPINE1 P05121 1/20 0.43
RAB9A P51151 1/20 0.43
MDH2 P40926 2/20 0.39
RARB P10826 3/20 0.39
RARG P13631 3/20 0.39
RARA P10276 2/20 0.39
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2707858 0.93 SERPINE1 (0.47) HIF1AEPAS1MEN1KMT2ASERPINE1
SCHEMBL2710156 0.92 HIF1A (0.48) HIF1AEPAS1MEN1KMT2ASERPINE1
SCHEMBL2710041 0.86 RARB (0.39) HIF1AEPAS1RARBRARGRARA
SCHEMBL2707051 0.84 SERPINE1 (0.47) HIF1AEPAS1MEN1KMT2ASERPINE1
SCHEMBL2708795 0.84 HIF1A (0.49) HIF1AEPAS1MEN1KMT2ASERPINE1
SCHEMBL2707830 0.83 HIF1A (0.47) HIF1AEPAS1MEN1KMT2ASERPINE1
SCHEMBL2709793 0.82 RARB (0.38) MEN1KMT2ARARBRARGRARA
SCHEMBL2709552 0.81 HIF1A (0.48) HIF1AEPAS1MEN1KMT2ASERPINE1
SCHEMBL2709279 0.81 MMP13 (0.36) RARBRARGRARACYP3A4MMP13
SCHEMBL19362904 0.80 MEN1 (0.55) HIF1AEPAS1MEN1KMT2ASERPINE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2000510-B1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM SUMITOMO BAKELITE CO (JP) 2012-05-02 EP disclosed
US-7863347-B2 Resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2011-01-04 US disclosed
US-7652125-B2 Resin composition, polyimide resin composition, polybenzoxazole resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2010-01-26 US disclosed
US-20090118431-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE COMPANY, LTD (JP) 2009-05-07 US disclosed
EP-2000510-A1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM Sumitomo Bakelite Company, Ltd. (JP) 2008-12-10 EP disclosed
US-20080255335-A1 Resin Composition, Polyimide Resin Composition, Polybenzoxazole Resin Composition, Varnish, Resin Film and Semiconductor Device Using the Same SUMITOMO BAKELITE COMPANY LTD. (JP) 2008-10-16 US disclosed
EP-1813637-A1 RESIN COMPOSITION, POLYIMIDE RESIN COMPOSITION, POLY- BENZOXAZOLE RESIN COMPOSITION, VARNISHES, RESIN FILMS AND SEMICONDUCTOR DEVICES MADE BY USING THE SAME Sumitomo Bakelite Company, Limited (JP) 2007-08-01 EP disclosed