Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17662444 | 0.92 | ALDH1A1 (0.33) | ALDH1A1MAPT | |
| SCHEMBL12793199 | 0.80 | ALDH1A1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL19169705 | 0.79 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL12640144 | 0.77 | ALDH1A1 (0.34) | ALDH1A1MAPT | |
| SCHEMBL14982939 | 0.75 | NAMPT (0.32) | ALDH1A1MAPT | |
| SCHEMBL22021683 | 0.75 | NAMPT (0.32) | — | |
| SCHEMBL3088181 | 0.75 | MVD (0.41) | ALDH1A1MAPT | |
| SCHEMBL22820092 | 0.75 | CNR1 (0.38) | ALDH1A1MAPT | |
| SCHEMBL20129897 | 0.75 | ALDH1A1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL12126184 | 0.75 | MAPT (0.33) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240218011-A1 | GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF | FIREFLY BIO, INC. | 2024-07-04 | — | — | US | disclosed |
| US-20240067640-A1 | PHENYL MALEIMIDE LINKER AGENTS | FIREFLY BIO, INC. | 2024-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240218011-A1 | GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF | NR3C1, NR3C2, MC2R | ALDH1A1 3778/4885MAPT 3713/4885 |
| US-20240067640-A1 | PHENYL MALEIMIDE LINKER AGENTS | TPX2, H1-4, MAPT | ALDH1A1 4502/4885MAPT 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.