Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27104908 | 0.88 | CCKBR (0.41) | CCKBRECE1BMP1SIRT5 | |
| SCHEMBL27104478 | 0.87 | CCKBR (0.41) | CCKBRPSMB8PSMB5ECE1BMP1 | |
| SCHEMBL27105102 | 0.86 | CCKBR (0.40) | CCKBRECE1BMP1SIRT5 | |
| SCHEMBL12010939 | 0.84 | MMP2 (0.39) | CCKBRPSMB8PSMB5BMP1 | |
| SCHEMBL27105101 | 0.84 | CCKBR (0.44) | CCKBRECE1BMP1 | |
| SCHEMBL27103298 | 0.83 | CCKBR (0.43) | CCKBRBMP1 | |
| SCHEMBL22316575 | 0.80 | FOLH1 (0.55) | BMP1 | |
| SCHEMBL22315883 | 0.79 | BMP1 (0.42) | CCKBRBMP1SIRT5 | |
| SCHEMBL27104138 | 0.79 | BMP1 (0.56) | BMP1 | |
| SCHEMBL27103253 | 0.79 | CCKBR (0.40) | CCKBRBMP1SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067640-A1 | PHENYL MALEIMIDE LINKER AGENTS | FIREFLY BIO, INC. | 2024-02-29 | — | — | US | disclosed |
| US-20240067640-A1 | PHENYL MALEIMIDE LINKER AGENTS | FIREFLY BIO, INC. | 2024-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067640-A1 | PHENYL MALEIMIDE LINKER AGENTS | TPX2, H1-4, MAPT | CCKBR 768/4885PSMB8 386/4885PSMB5 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.