Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.63 |
| ▸ | RAB9A | P51151 | 10/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.63 |
| ▸ | HPGD | P15428 | 8/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.55 |
| ▸ | TP53 | P04637 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27050400 | 0.90 | NPC1 (0.56) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL23473649 | 0.90 | NPC1 (0.48) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL23473690 | 0.90 | NPC1 (0.48) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL27049241 | 0.87 | NPC1 (0.45) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL23473654 | 0.86 | NPC1 (0.51) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL27107585 | 0.85 | SMN1; SMN2 (0.59) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL23473647 | 0.84 | NPC1 (0.51) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL15681413 | 0.84 | SMN1; SMN2 (0.88) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL436386 | 0.84 | NPC1 (0.76) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL23079757 | 0.84 | NPC1 (0.47) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240074312-A1 | PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) | 2024-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240074312-A1 | PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | MCM6, MCM2, SOD1 | NPC1 2193/4885RAB9A 1874/4885KDM4E 3635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.