Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9113382 | 0.81 | LMNA (0.46) | LMNAFAAHMGLLTSHRMAPT | |
| SCHEMBL9113376 | 0.81 | LMNA (0.46) | LMNAFAAHMGLLTSHRMAPT | |
| SCHEMBL12961052 | 0.81 | LMNA (0.37) | LMNATSHRMAPTALDH1A1 | |
| SCHEMBL514518 | 0.80 | FAAH (0.49) | LMNAFAAHMGLLTSHRMAPT | |
| SCHEMBL27844940 | 0.80 | LMNA (0.48) | LMNAFAAHMGLLTSHRMAPT | |
| SCHEMBL28269587 | 0.80 | LMNA (0.42) | LMNATSHRMAPTPGRADORA3 | |
| SCHEMBL19077703 | 0.79 | LMNA (0.50) | LMNATSHRMAPTLSSHTT | |
| SCHEMBL28127321 | 0.79 | LMNA (0.50) | LMNATSHRMAPTLSSHTT | |
| SCHEMBL28332773 | 0.77 | LMNA (0.55) | LMNAFAAHMAPTPGRADORA3 | |
| SCHEMBL14899320 | 0.77 | LMNA (0.50) | LMNAFAAHTSHRMAPTPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067634-A1 | INHIBITORS OF NEF DOWNMODULATION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067634-A1 | INHIBITORS OF NEF DOWNMODULATION | HLA-DRB1, CD74, MICA | LMNA 3674/4885FAAH 1324/4885MGLL 2314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.