Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27116713 | 0.87 | ITGB3 (0.43) | SMN1; SMN2MAPTKDM4ELMNAHTT | |
| SCHEMBL27114914 | 0.85 | MAPT (0.51) | SMN1; SMN2GAAMAPTKDM4EMAPK1 | |
| SCHEMBL27116715 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2GAAMAPTALOX15ALOX12 | |
| SCHEMBL27114134 | 0.83 | TP53 (0.47) | SMN1; SMN2GAAMAPTALOX15ALOX12 | |
| SCHEMBL27119572 | 0.78 | KMT2A (0.44) | SMN1; SMN2GAAMAPTALOX15KDM4E | |
| SCHEMBL27116714 | 0.73 | F2 (0.41) | GAAMAPTALOX15ALOX12KDM4E | |
| SCHEMBL27114555 | 0.73 | ALDH1A1 (0.42) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL27114132 | 0.73 | F2 (0.41) | SMN1; SMN2GAAMAPTLMNAHTT | |
| SCHEMBL16181284 | 0.72 | PARP1 (0.39) | TSHRCYP2C19CA1CA2 | |
| SCHEMBL24891910 | 0.72 | MAPT (0.53) | SMN1; SMN2MAPTALOX15KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240066135-A1 | DRUG CONJUGATES AND USES THEREOF | SUPERTRANS MEDICAL LTD (IL) | 2024-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066135-A1 | DRUG CONJUGATES AND USES THEREOF | SLC7A1, ABCB11, SLC1A5 | SMN1; SMN2 4664/4885GAA 350/4885MAPT 2991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.