Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.53 |
| ▸ | CDK2 | P24941 | 2/20 | 0.53 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.51 |
| ▸ | CDK1 | P06493 | 2/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.51 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.47 |
| ▸ | CAMKK2 | Q96RR4 | 5/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27116074 | 0.91 | PIK3CG (0.48) | CDK4CDK2CCNB2CDK1CCNB1 | |
| SCHEMBL27115952 | 0.83 | PIK3CG (0.50) | CDK2PIK3CGPIK3CAPIK3CBMEN1 | |
| SCHEMBL27116075 | 0.82 | CCNB2 (0.55) | CDK4CDK2CCNB2CDK1CCNB1 | |
| SCHEMBL27116600 | 0.82 | ABL1 (0.57) | PIK3CGPIK3CAPIK3CBMEN1NPC1 | |
| SCHEMBL27116135 | 0.81 | GSK3B (0.53) | CDK2PIK3CGPIK3CAGSK3BPIK3CB | |
| SCHEMBL27115275 | 0.80 | PIK3CG (0.55) | CDK4CDK2PIK3CGPIK3CAGSK3B | |
| SCHEMBL27148413 | 0.80 | IGF1R (0.49) | CDK4CDK2CDK1CCNB1PIK3CG | |
| SCHEMBL27116528 | 0.80 | PIK3CG (0.64) | CDK4CDK2PIK3CGPIK3CAGSK3B | |
| SCHEMBL27115955 | 0.77 | MKNK1 (0.54) | CDK2PIK3CGPIK3CAPIK3CBMEN1 | |
| SCHEMBL27115445 | 0.77 | PIK3CG (0.66) | CDK2CCNB2CDK1CCNB1CCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | claimed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |