SCHEMBL27118935

SCHEMBL27118935

COc1cc2c(cc1Br)-c1c(c(C(=O)N(C)C(C)(C)C)nn1-c1cc(Cl)cc(Cl)c1)C2

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PDE7A Q13946 1/20 0.38
▸ PDE3A Q14432 1/20 0.38
▸ PDE10A Q9Y233 1/20 0.38
▸ CA12 O43570 1/20 0.37
▸ CA2 P00918 1/20 0.37
▸ CA9 Q16790 1/20 0.37
▸ RAD52 P43351 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.32
▸ PDGFRB P09619 1/20 0.32
▸ CNR1 P21554 1/20 0.31
▸ CNR2 P34972 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30759620 0.93 PDE7A (0.40) PDE7APDE3APDE10ACA12CA2
SCHEMBL30759622 0.93 PDE7A (0.40) PDE7APDE3APDE10ACA12CA2
SCHEMBL27119529 0.93 PDE7A (0.40) PDE7APDE3APDE10ACA12CA2
SCHEMBL27118937 0.86 CA12 (0.36) PDE7APDE3APDE10ACA12CA2
SCHEMBL27119215 0.86 PDE7A (0.38) PDE7APDE3APDE10ACA12CA2
SCHEMBL27118754 0.85 CA12 (0.39) CA12CA2CA9RAD52PDGFRB
SCHEMBL30885909 0.85 NR1H4 (0.35) PDE7APDE3APDE10ARAD52ALDH1A1
SCHEMBL17381611 0.85 NR1H4 (0.35) PDE7APDE3APDE10ARAD52ALDH1A1
SCHEMBL30759633 0.85 PTGS2 (0.40) PDE7APDE3APDE10AALDH1A1LMNA
SCHEMBL27118151 0.85 PTGS2 (0.40) PDE7APDE3APDE10AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR PDE7A 400/4885PDE3A 386/4885PDE10A 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback