Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | TEK | Q02763 | 1/20 | 0.47 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.46 |
| ▸ | BCL6 | P41182 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 3/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27112164 | 0.81 | TEK (0.51) | TEKTBK1BCL6FGFR2FGFR3 | |
| SCHEMBL27116469 | 0.79 | PRKCA (0.63) | MEN1KMT2ACDK5CAMK2D | |
| SCHEMBL28185425 | 0.78 | BCL6 (0.61) | TEKTBK1BCL6FGFR3MEN1 | |
| SCHEMBL27843906 | 0.78 | PIK3CA (0.53) | TBK1MEN1USP2KMT2ACDK9 | |
| SCHEMBL14214623 | 0.77 | KDR (0.55) | TBK1MEN1KMT2ACDK9CSF1R | |
| SCHEMBL27890451 | 0.76 | CYP1A2 (0.55) | TEKTBK1FGFR2FGFR3MEN1 | |
| SCHEMBL2459757 | 0.74 | TEK (0.64) | TEKBCL6FGFR2FGFR3USP2 | |
| SCHEMBL27824876 | 0.73 | TBK1 (0.47) | TBK1MEN1USP2KMT2ABRAF | |
| SCHEMBL2330210 | 0.73 | TBK1 (0.51) | TBK1FGFR2FGFR3MEN1USP2 | |
| SCHEMBL29636445 | 0.72 | KMT2A (0.54) | MEN1USP2KMT2AACP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |