Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30759597 | 1.00 | PDE7A (0.36) | PDE7APDE3APDE10ARAD52CYP11B2 | |
| SCHEMBL27118975 | 0.94 | PDE7A (0.35) | PDE7APDE3APDE10ACYP11B2CYP11B1 | |
| SCHEMBL30759484 | 0.94 | PDE7A (0.35) | PDE7APDE3APDE10ACYP11B2CYP11B1 | |
| SCHEMBL27119953 | 0.89 | CCNA2 (0.38) | RAD52CYP11B2CYP11B1CCNA2CDK2 | |
| SCHEMBL30759574 | 0.89 | CCNA2 (0.38) | RAD52CYP11B2CYP11B1CCNA2CDK2 | |
| SCHEMBL31236967 | 0.88 | ABL1 (0.33) | CYP11B2CYP11B1GRM5GPR119BRD4 | |
| SCHEMBL30759625 | 0.88 | PDE7A (0.36) | PDE7APDE3APDE10ARAD52CYP11B2 | |
| SCHEMBL27119776 | 0.88 | PDE7A (0.36) | PDE7APDE3APDE10ARAD52CYP11B2 | |
| SCHEMBL30759534 | 0.87 | PDE7A (0.35) | PDE7APDE3APDE10ACYP11B2CYP11B1 | |
| SCHEMBL17381580 | 0.87 | NR1H4 (0.34) | GRM5GPR119SSTR2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044778-A2 | NOVEL MODULATORS OF FSHR AND USES THEREOF | CELMATIX INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024044778-A2 | NOVEL MODULATORS OF FSHR AND USES THEREOF | CELMATIX INC. (US) | 2024-02-29 | — | — | WO | disclosed |