SCHEMBL30759534

SCHEMBL30759534

COc1cc2c(cc1-c1cncc(C#N)c1)-c1c(c(C(=O)N(C)C(C)(C)C)nn1-c1cc(Cl)cc(Cl)c1)SC2

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ PDE7A Q13946 1/20 0.35
▸ PDE3A Q14432 1/20 0.35
▸ PDE10A Q9Y233 1/20 0.35
▸ PTGS2 P35354 3/20 0.34
▸ PTGS1 P23219 1/20 0.34
▸ POLQ O75417 1/20 0.32
▸ GRM5 P41594 1/20 0.31
▸ CYP11B1 P15538 1/20 0.31
▸ CYP11B2 P19099 1/20 0.31
▸ GPR119 Q8TDV5 1/20 0.31
▸ SSTR2 P30874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27118212 1.00 PDE7A (0.35) PDE7APDE3APDE10APTGS2PTGS1
SCHEMBL30759559 0.88 PTGS2 (0.35) PDE7APDE3APDE10APTGS2PTGS1
SCHEMBL27118239 0.88 PTGS2 (0.35) PDE7APDE3APDE10APTGS2PTGS1
SCHEMBL27119775 0.87 PDE7A (0.36) PDE7APDE3APDE10AGRM5CYP11B1
SCHEMBL27118975 0.87 PDE7A (0.35) PDE7APDE3APDE10AGRM5CYP11B1
SCHEMBL30759597 0.87 PDE7A (0.36) PDE7APDE3APDE10AGRM5CYP11B1
SCHEMBL30759484 0.87 PDE7A (0.35) PDE7APDE3APDE10AGRM5CYP11B1
SCHEMBL30759633 0.83 PTGS2 (0.40) PDE7APDE3APDE10APTGS2PTGS1
SCHEMBL27118151 0.83 PTGS2 (0.40) PDE7APDE3APDE10APTGS2PTGS1
SCHEMBL27118272 0.82 PTGS2 (0.38) PDE7APDE3APDE10APTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR PDE7A 400/4885PDE3A 386/4885PDE10A 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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