SCHEMBL30759597

SCHEMBL30759597

COc1cc2c(cc1-c1cncc(C#N)c1)-c1c(c(C(=O)N(C)C(C)(C)C)nn1-c1cc(Cl)cc(Cl)c1)CC2

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ PDE7A Q13946 1/20 0.36
▸ PDE3A Q14432 1/20 0.36
▸ PDE10A Q9Y233 1/20 0.36
▸ RAD52 P43351 1/20 0.35
▸ CYP11B2 P19099 3/20 0.34
▸ CYP11B1 P15538 2/20 0.34
▸ GRM5 P41594 1/20 0.32
▸ GPR119 Q8TDV5 1/20 0.32
▸ CCNA2 P20248 1/20 0.32
▸ CDK2 P24941 1/20 0.32
▸ CCNA1 P78396 1/20 0.32
▸ BRD4 O60885 1/20 0.32
▸ CREBBP Q92793 1/20 0.32
▸ SSTR2 P30874 1/20 0.31
▸ IKBKB O14920 1/20 0.31
▸ ABL1 P00519 2/20 0.30
▸ CYP3A4 P08684 1/20 0.30
▸ CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27119775 1.00 PDE7A (0.36) PDE7APDE3APDE10ARAD52CYP11B2
SCHEMBL27118975 0.94 PDE7A (0.35) PDE7APDE3APDE10ACYP11B2CYP11B1
SCHEMBL30759484 0.94 PDE7A (0.35) PDE7APDE3APDE10ACYP11B2CYP11B1
SCHEMBL27119953 0.89 CCNA2 (0.38) RAD52CYP11B2CYP11B1CCNA2CDK2
SCHEMBL30759574 0.89 CCNA2 (0.38) RAD52CYP11B2CYP11B1CCNA2CDK2
SCHEMBL31236967 0.88 ABL1 (0.33) CYP11B2CYP11B1GRM5GPR119BRD4
SCHEMBL30759625 0.88 PDE7A (0.36) PDE7APDE3APDE10ARAD52CYP11B2
SCHEMBL27119776 0.88 PDE7A (0.36) PDE7APDE3APDE10ARAD52CYP11B2
SCHEMBL30759534 0.87 PDE7A (0.35) PDE7APDE3APDE10ACYP11B2CYP11B1
SCHEMBL17381580 0.87 NR1H4 (0.34) GRM5GPR119SSTR2ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR PDE7A 400/4885PDE3A 386/4885PDE10A 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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