Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27124438 | 0.86 | KDM4E (0.38) | — | |
| SCHEMBL27113565 | 0.85 | — | — | |
| SCHEMBL27122864 | 0.85 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL25993259 | 0.81 | THRB (0.33) | — | |
| SCHEMBL24421587 | 0.79 | THRB (0.39) | — | |
| SCHEMBL27116428 | 0.79 | LMNA (0.32) | — | |
| SCHEMBL27117690 | 0.79 | S1PR1 (0.32) | SIGMAR1 | |
| SCHEMBL27118127 | 0.79 | CHRM1 (0.35) | SIGMAR1 | |
| SCHEMBL24421581 | 0.79 | THRB (0.41) | — | |
| SCHEMBL27122537 | 0.79 | SIGMAR1 (0.32) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076650-B1 | 3-(5-METHOXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2024-02-28 | — | — | EP | disclosed |