SCHEMBL2712918

SCHEMBL2712918

COCCOCCOCCP(=O)(C(=O)c1c(C)cc(C)cc1C)C(=O)c1c(C)cc(C)cc1C

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 1/20 0.37
HPGD P15428 3/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TAS1R3 Q7RTX0 4/20 0.33
TAS1R1 Q7RTX1 4/20 0.33
TAS1R2 Q8TE23 4/20 0.33
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 3/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17827614 0.86 CRHR1 (0.33) CRHR1HPGDMEN1KMT2ALMNA
SCHEMBL8532885 0.85 MAPT (0.40) MEN1KMT2ALMNATAS1R3TAS1R1
SCHEMBL1038469 0.83 CRHR1 (0.34) CRHR1HPGDMEN1KMT2ALMNA
SCHEMBL2886656 0.83 CRHR1 (0.34) CRHR1HPGDMEN1KMT2ALMNA
SCHEMBL15823939 0.82 CRHR1 (0.37) CRHR1HPGDMEN1KMT2ALMNA
SCHEMBL29744628 0.82 CRHR1 (0.37) CRHR1HPGDMEN1KMT2ALMNA
SCHEMBL17532270 0.82 CRHR1 (0.37) CRHR1HPGDMEN1KMT2ALMNA
SCHEMBL1037233 0.79 CETP (0.38) MEN1KMT2ALMNASMN1; SMN2ALDH1A1
SCHEMBL28655188 0.79 MEN1 (0.37) CRHR1HPGDMEN1KMT2ALMNA
SCHEMBL1035616 0.79 KMT2A (0.40) HPGDMEN1KMT2ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921444-B2 Process for the modification of polymers, in particular polymer nanoparticles MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2014-12-30 US claimed
US-8921442-B2 Ultra fast process for the preparation of polymer nanoparticles MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E. V. (DE) 2014-12-30 US claimed
US-20130261210-A1 ULTRA FAST PROCESS FOR THE PREPARATION OF POLYMER NANOPARTICLES MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2013-10-03 US claimed
US-20130261211-A1 PROCESS FOR THE MODIFICATION OF POLYMERS, IN PARTICULAR POLYMER NANOPARTICLES MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2013-10-03 US claimed
EP-2630163-A1 ULTRA FAST PROCESS FOR THE PREPARATION OF POLYMER NANOPARTICLES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2013-08-28 EP claimed
EP-2630164-A1 PROCESS FOR THE MODIFICATION OF POLYMERS, IN PARTICULAR POLYMER NANOPARTICLES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2013-08-28 EP claimed
WO-2012052148-A1 ULTRA FAST PROCESS FOR THE PREPARATION OF POLYMER NANOPARTICLES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2012-04-26 WO claimed
WO-2012052147-A1 PROCESS FOR THE MODIFICATION OF POLYMERS, IN PARTICULAR POLYMER NANOPARTICLES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2012-04-26 WO claimed
EP-2630163-B1 ULTRA FAST PROCESS FOR THE PREPARATION OF POLYMER NANOPARTICLES MAX PLANCK GESELLSCHAFT (DE) 2018-05-16 EP disclosed
US-9555583-B1 Fabrication of neural interfaces using 3D projection micro-stereolithography SANDIA CORPORATION (US) 2017-01-31 US disclosed
US-8921444-B2 Process for the modification of polymers, in particular polymer nanoparticles MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2014-12-30 US disclosed
US-8921442-B2 Ultra fast process for the preparation of polymer nanoparticles MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E. V. (DE) 2014-12-30 US disclosed
US-20130261210-A1 ULTRA FAST PROCESS FOR THE PREPARATION OF POLYMER NANOPARTICLES MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2013-10-03 US disclosed
EP-2630163-A1 ULTRA FAST PROCESS FOR THE PREPARATION OF POLYMER NANOPARTICLES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2013-08-28 EP disclosed
EP-2630164-A1 PROCESS FOR THE MODIFICATION OF POLYMERS, IN PARTICULAR POLYMER NANOPARTICLES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2013-08-28 EP disclosed
WO-2012052147-A1 PROCESS FOR THE MODIFICATION OF POLYMERS, IN PARTICULAR POLYMER NANOPARTICLES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2012-04-26 WO disclosed
WO-2012052148-A1 ULTRA FAST PROCESS FOR THE PREPARATION OF POLYMER NANOPARTICLES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2012-04-26 WO disclosed