SCHEMBL15823939

SCHEMBL15823939

COCCOCCOCCOP(=O)(C(=O)c1c(C)cc(C)cc1C)C(=O)c1c(C)cc(C)cc1C

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 1/20 0.37
HPGD P15428 3/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TAS1R3 Q7RTX0 4/20 0.33
TAS1R1 Q7RTX1 4/20 0.33
TAS1R2 Q8TE23 4/20 0.33
CA2 P00918 1/20 0.32
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32
KDM4E B2RXH2 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29744628 1.00 CRHR1 (0.37) CRHR1HPGDMEN1KMT2ALMNA
SCHEMBL17532270 1.00 CRHR1 (0.37) CRHR1HPGDMEN1KMT2ALMNA
SCHEMBL17532272 0.95 MEN1 (0.36) CRHR1HPGDMEN1KMT2ALMNA
SCHEMBL15825228 0.90 HTR1A (0.38) CRHR1HPGDMEN1KMT2ALMNA
SCHEMBL20843208 0.90 MEN1 (0.36) CRHR1HPGDMEN1KMT2ALMNA
SCHEMBL15823941 0.85 HSD17B10 (0.33) HPGDMEN1KMT2ALMNASMN1; SMN2
SCHEMBL15839083 0.83 MEN1 (0.40) CRHR1HPGDMEN1KMT2ALMNA
SCHEMBL19270328 0.82 LPAR1 (0.35) HPGDMEN1KMT2ALMNASMN1; SMN2
SCHEMBL2712918 0.82 CRHR1 (0.37) CRHR1HPGDMEN1KMT2ALMNA
SCHEMBL29411892 0.81 TAS1R3 (0.33) CRHR1MEN1KMT2ASMN1; SMN2TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2935289-B1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS IGM GROUP B V (NL) 2019-06-26 EP disclosed
EP-3459957-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS IGM Group B.V. (NL) 2019-03-27 EP disclosed
US-10040810-B2 Derivatives of bisacylphosphinic acid, their preparation and use as photoinitiators BASF SE (DE) 2018-08-07 US disclosed
US-10040810-B2 Derivatives of bisacylphosphinic acid, their preparation and use as photoinitiators BASF SE (DE) 2018-08-07 US disclosed
US-10040810-B2 Derivatives of bisacylphosphinic acid, their preparation and use as photoinitiators BASF SE (DE) 2018-08-07 US disclosed
US-20160039851-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS IGM GROUP B.V. (NL) 2016-02-11 US disclosed
US-20160039851-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS IGM GROUP B.V. (NL) 2016-02-11 US disclosed
US-20160039851-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS IGM GROUP B.V. (NL) 2016-02-11 US disclosed
EP-2935289-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS BASF SE (DE) 2015-10-28 EP disclosed
WO-2014095724-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS BASF SE (DE) 2014-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160039851-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS ARSA, ACSL6, RER1 CRHR1 3228/4885HPGD 4526/4885MEN1 1781/4885
US-10040810-B2 Derivatives of bisacylphosphinic acid, their preparation and use as photoinitiators ARSA, RER1, ACSL6 CRHR1 3808/4885HPGD 4618/4885MEN1 1230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.