Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484978 | 0.82 | NPC1 (0.44) | CETPLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2712918 | 0.79 | CRHR1 (0.37) | LMNAMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL1037982 | 0.79 | ALDH1A1 (0.45) | LMNAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7625246 | 0.79 | LMNA (0.41) | LMNAMEN1KMT2AATMSMN1; SMN2 | |
| SCHEMBL8532885 | 0.77 | MAPT (0.40) | LMNAMEN1KMT2AATMKDM4E | |
| SCHEMBL1038051 | 0.75 | ALDH1A1 (0.41) | LMNAMEN1KMT2AATMSMN1; SMN2 | |
| SCHEMBL13811173 | 0.74 | CETP (0.44) | CETPLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28655188 | 0.73 | MEN1 (0.37) | LMNAMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL1035616 | 0.73 | KMT2A (0.40) | LMNAMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL2062968 | 0.73 | L3MBTL1 (0.42) | MEN1KMT2AATMSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814891-B1 | BISACYLPHOSPHANES AND THEIR USE AS PHOTOINITIATORS; PROCESS FOR PREPARING ACYLPHOSPHANES | BASF SE (DE) | 2011-01-26 | — | — | EP | disclosed |
| EP-1814891-B1 | BISACYLPHOSPHANES AND THEIR USE AS PHOTOINITIATORS; PROCESS FOR PREPARING ACYLPHOSPHANES | BASF SE (DE) | 2011-01-26 | — | — | EP | disclosed |
| US-7687657-B2 | Process for preparing acylphosphanes and derivatives thereof | CIBA SPECIALITY CHEMICALS CORPORATION (US) | 2010-03-30 | — | — | US | disclosed |
| US-7687657-B2 | Process for preparing acylphosphanes and derivatives thereof | CIBA SPECIALITY CHEMICALS CORPORATION (US) | 2010-03-30 | — | — | US | disclosed |
| US-7687657-B2 | Process for preparing acylphosphanes and derivatives thereof | CIBA SPECIALITY CHEMICALS CORPORATION (US) | 2010-03-30 | — | — | US | disclosed |
| US-20080004464-A1 | Process for Preparing Acylphosphanes and Derivatives Thereof | IGM GROUP B.V. (NL) | 2008-01-03 | — | — | US | disclosed |
| US-20080004464-A1 | Process for Preparing Acylphosphanes and Derivatives Thereof | IGM GROUP B.V. (NL) | 2008-01-03 | — | — | US | disclosed |
| US-20080004464-A1 | Process for Preparing Acylphosphanes and Derivatives Thereof | IGM GROUP B.V. (NL) | 2008-01-03 | — | — | US | disclosed |
| EP-1814891-A1 | PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006056541-A1 | PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004464-A1 | Process for Preparing Acylphosphanes and Derivatives Thereof | ME2, ME3, MEP1A | CETP 577/4885LMNA 1081/4885MEN1 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.