Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.54 |
| ▸ | NPC1 | O15118 | 9/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.50 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19632762 | 0.85 | STAT3 (0.61) | RAB9ANPC1SMN1; SMN2RXFP1TP53 | |
| SCHEMBL27135218 | 0.85 | CYP1A2 (0.55) | RAB9ANPC1HSD17B10PKMALOX15 | |
| SCHEMBL10287242 | 0.84 | ALDH1A1 (0.46) | RAB9ANPC1SMN1; SMN2RXFP1CRHBP | |
| SCHEMBL24072396 | 0.84 | STAT3 (0.44) | RAB9ANPC1SMN1; SMN2RXFP1TP53 | |
| SCHEMBL24074429 | 0.84 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2RXFP1TP53 | |
| SCHEMBL24074140 | 0.84 | NPC1 (0.56) | RAB9ANPC1SMN1; SMN2TP53HSD17B10 | |
| SCHEMBL27134428 | 0.84 | NPC1 (0.62) | RAB9ANPC1RXFP1HSD17B10MEN1 | |
| SCHEMBL27134429 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2TP53STIM1ORAI1PKM | |
| SCHEMBL27134435 | 0.83 | LMNA (0.48) | TP53MEN1KMT2AGAA | |
| SCHEMBL24072305 | 0.82 | CCNE1 (0.49) | RAB9ANPC1SMN1; SMN2TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, MDM2 | RAB9A 3280/4885NPC1 3949/4885SMN1; SMN2 2621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.