Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28362604 | 0.83 | POLB (0.59) | ALDH1A1POLBMEN1PKMNPY1R | |
| SCHEMBL5327852 | 0.83 | ALDH1A1 (0.68) | ALDH1A1POLBMEN1PKMNPY1R | |
| SCHEMBL6634172 | 0.80 | MAPT (0.56) | ALDH1A1POLBMEN1PKMNPY1R | |
| SCHEMBL28524078 | 0.79 | MEN1 (0.58) | ALDH1A1POLBMEN1PKMNPY1R | |
| SCHEMBL26630415 | 0.79 | MAPT (0.56) | ALDH1A1POLBMEN1PKMNPY1R | |
| SCHEMBL6184844 | 0.78 | ALDH1A1 (0.53) | ALDH1A1POLBMEN1PKMNPY1R | |
| SCHEMBL8589692 | 0.78 | ALDH1A1 (0.53) | ALDH1A1POLBMEN1PKMNPY1R | |
| SCHEMBL10915060 | 0.77 | ALDH1A1 (0.63) | ALDH1A1POLBMEN1PKMNPY1R | |
| SCHEMBL6635342 | 0.77 | KMT2A (0.52) | ALDH1A1POLBMEN1PKMNPY1R | |
| SCHEMBL7354442 | 0.77 | ESR1 (0.53) | ALDH1A1POLBMEN1PKMNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208998-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | UNIVERSITAT DE BARCELONA (ES) | 2024-06-27 | — | — | US | disclosed |
| EP-4326262-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | Fundació Privada Institut d'Investigació Oncològica de Vall Hebron (ES) | 2024-02-28 | — | — | EP | disclosed |
| CN-117320715-A | Compounds for the treatment of hyperproliferative diseases | 瓦尔希伯伦私人肿瘤研究基金会 | 2023-12-29 | — | — | CN | disclosed |
| WO-2022223704-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | FUNDACIÓ PRIVADA INSTITUT D'INVESTIGACIÓ ONCOLÒGICA DE VALL HEBRON (ES) | 2022-10-27 | — | — | WO | disclosed |
| EP-4079304-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron (ES) | 2022-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208998-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | VHL, PCNA, HRAS | ALDH1A1 1062/4885POLB 399/4885MEN1 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.