Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17581276 | 0.82 | KDM4E (0.33) | — | |
| SCHEMBL11396782 | 0.82 | DHFR (0.54) | DHFR | |
| SCHEMBL22895290 | 0.81 | KDM4E (0.32) | — | |
| SCHEMBL7724215 | 0.81 | LMNA (0.69) | LMNA | |
| SCHEMBL27153028 | 0.77 | ALDH1A1 (0.36) | LMNA | |
| SCHEMBL30891184 | 0.77 | ALDH1A1 (0.36) | LMNA | |
| SCHEMBL21593668 | 0.77 | CSNK1A1 (0.43) | LMNACSNK1A1CLK4DHFR | |
| SCHEMBL25323208 | 0.73 | TLR8 (0.45) | CSNK1A1CLK4 | |
| SCHEMBL30068026 | 0.73 | TLR8 (0.45) | CSNK1A1CLK4 | |
| SCHEMBL30042167 | 0.72 | TLR8 (0.46) | CSNK1A1CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044731-A1 | DIAZEPINO-THIENO-QUINOXALINE COMPOUNDS AND THEIR USE IN THERAPY | MATCHPOINT THERAPEUTICS INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024044731-A1 | DIAZEPINO-THIENO-QUINOXALINE COMPOUNDS AND THEIR USE IN THERAPY | MATCHPOINT THERAPEUTICS INC. (US) | 2024-02-29 | — | — | WO | disclosed |