SCHEMBL27140488

SCHEMBL27140488

Cc1cnc(-c2cc(-c3ccccc3)c(C)cc2C)cc1CC(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA2B P29275 1/20 0.38
ADORA1 P30542 1/20 0.38
LDHA P00338 1/20 0.38
SGK1 O00141 1/20 0.34
CAMKK2 Q96RR4 1/20 0.34
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 2/20 0.33
ESR2 Q92731 1/20 0.33
NPC1 O15118 1/20 0.33
PDGFRB P09619 1/20 0.33
KDR P35968 1/20 0.33
FLT3 P36888 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
DHFR P00374 1/20 0.33
BRS3 P32247 1/20 0.32
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27424197 0.92 ADORA3 (0.38) ADORA3ADORA2AADORA2BADORA1LDHA
SCHEMBL27424196 0.89 LDHA (0.40) ADORA3ADORA2AADORA2BADORA1LDHA
SCHEMBL18730284 0.86 LDHA (0.46) ADORA3ADORA2AADORA2BADORA1LDHA
SCHEMBL23562222 0.85 ADORA3 (0.40) ADORA3ADORA2AADORA2BADORA1LDHA
SCHEMBL26382639 0.85 LDHA (0.43) ADORA3ADORA2AADORA1LDHACYP11B1
SCHEMBL26050424 0.82 LDHA (0.47) ADORA3ADORA2AADORA1LDHACYP11B1
SCHEMBL19373370 0.81 CYP1A2 (0.42) NPC1RAB9ASMN1; SMN2CYP3A4ALOX5AP
SCHEMBL26316040 0.81 LDHA (0.38) LDHACYP11B1CYP11B2ESR2NPC1
SCHEMBL26714895 0.80 LDHA (0.41) ADORA3ADORA2AADORA2BADORA1LDHA
SCHEMBL25983007 0.80 ALOX5AP (0.44) KDRCYP3A4ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP ADORA3 2279/4885ADORA2A 1805/4885ADORA2B 2959/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG ADORA3 2166/4885ADORA2A 1687/4885ADORA2B 2232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.