SCHEMBL27424196

SCHEMBL27424196

Cc1cc(-c2cc(-c3ccccc3)c(C)cc2C)ncc1CC(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.40
ADORA3 P0DMS8 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA2B P29275 1/20 0.38
ADORA1 P30542 1/20 0.38
SGK1 O00141 1/20 0.34
CAMKK2 Q96RR4 1/20 0.34
RAB9A P51151 2/20 0.33
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 2/20 0.33
ESR2 Q92731 1/20 0.33
NPC1 O15118 1/20 0.33
PDGFRB P09619 1/20 0.33
KDR P35968 1/20 0.33
FLT3 P36888 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
S1PR1 P21453 2/20 0.33
S1PR3 Q99500 2/20 0.33
AAK1 Q2M2I8 1/20 0.33
DHFR P00374 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27424197 0.92 ADORA3 (0.38) LDHAADORA3ADORA2AADORA2BADORA1
SCHEMBL27140488 0.89 ADORA3 (0.38) LDHAADORA3ADORA2AADORA2BADORA1
SCHEMBL18730297 0.86 LDHA (0.50) LDHAADORA3ADORA2AADORA2BADORA1
SCHEMBL25985109 0.85 ADORA3 (0.40) LDHAADORA3ADORA2AADORA2BADORA1
SCHEMBL24292237 0.85 LDHA (0.47) LDHAADORA3ADORA2AADORA1RAB9A
SCHEMBL27424200 0.83 LDHA (0.44) LDHAADORA3ADORA2AADORA2BADORA1
SCHEMBL23189495 0.81 CYP1A2 (0.42) RAB9ANPC1SMN1; SMN2AAK1KDM4E
SCHEMBL25444864 0.81 LDHA (0.40) LDHARAB9ACYP11B1CYP11B2ESR2
SCHEMBL25012097 0.79 LDHA (0.49) LDHAADORA3ADORA2AADORA1RAB9A
SCHEMBL26050424 0.79 LDHA (0.47) LDHAADORA3ADORA2AADORA1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG LDHA 581/4885ADORA3 2166/4885ADORA2A 1687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.