Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14441468 | 0.88 | KDM4E (0.48) | PLK1KMT2ALMNAHIF1AALDH1A1 | |
| SCHEMBL30966104 | 0.87 | MAPT (0.46) | MAOAMAOBMAPTLMNAL3MBTL1 | |
| SCHEMBL27433301 | 0.87 | MAPT (0.46) | MAOAMAOBMAPTLMNAL3MBTL1 | |
| SCHEMBL27433526 | 0.86 | MAPT (0.42) | PLA2G2AMAOAMAOBMAPTLMNA | |
| SCHEMBL27433446 | 0.86 | MAOB (0.43) | PLA2G2AMAOAMAOBMAPTLMNA | |
| SCHEMBL30966089 | 0.86 | MAOB (0.43) | PLA2G2AMAOAMAOBMAPTLMNA | |
| SCHEMBL18199320 | 0.83 | PLA2G2A (0.50) | PLA2G2AMAOAMAOBMAPTPLK1 | |
| SCHEMBL149036 | 0.83 | KDM4E (0.55) | PLA2G2AMAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL28281865 | 0.82 | PLA2G2A (0.47) | PLA2G2AMAOAMAOBMAPTPLK1 | |
| SCHEMBL12687065 | 0.81 | MAOA (0.51) | PLA2G2AMAOAMAOBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577537-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-07-02 | — | — | EP | disclosed |
| CN-120091998-A | Substituted bicyclic rings as HSET inhibitors | 默克专利股份公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2024042007-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | WO | disclosed |