Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.43 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30966089 | 1.00 | MAOB (0.43) | MAOBMAOAMAPTRAB9AALDH1A1 | |
| SCHEMBL27433526 | 0.97 | MAPT (0.42) | MAOBMAOAMAPTRAB9AALDH1A1 | |
| SCHEMBL27433301 | 0.96 | MAPT (0.46) | MAOBMAOAMAPTRAB9AALDH1A1 | |
| SCHEMBL30966104 | 0.96 | MAPT (0.46) | MAOBMAOAMAPTRAB9AALDH1A1 | |
| SCHEMBL27141409 | 0.86 | PLA2G2A (0.46) | MAOBMAOAMAPTALDH1A1LMNA | |
| SCHEMBL14441468 | 0.83 | KDM4E (0.48) | RAB9AALDH1A1LMNAKDM4ECYP1A2 | |
| SCHEMBL27433963 | 0.81 | MAPT (0.40) | MAOBMAOAMAPTRAB9AALDH1A1 | |
| SCHEMBL30966103 | 0.81 | MAPT (0.40) | MAOBMAOAMAPTRAB9AALDH1A1 | |
| SCHEMBL149036 | 0.81 | KDM4E (0.55) | MAPTRAB9AALDH1A1LMNAKDM4E | |
| SCHEMBL896633 | 0.81 | KDM4E (0.51) | RAB9AALDH1A1LMNAKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130341-A1 | BENZIMIDAZOLE DERIVATIVES FOR THE MODULATION OF STING | Aculeus Therapeutics Pty Ltd (AU) | 2024-06-27 | — | — | WO | disclosed |