Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27137179 | 0.84 | GPR119 (0.62) | KMT2AGPR119MEN1 | |
| SCHEMBL30020119 | 0.82 | GPR119 (0.48) | ALDH1A1KMT2AGPR119KDM4ELMNA | |
| SCHEMBL19834817 | 0.81 | GPR119 (0.49) | ALDH1A1KMT2AGPR119KDM4ELMNA | |
| SCHEMBL2389377 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KMT2AGPR119KDM4ELMNA | |
| SCHEMBL7459127 | 0.79 | ALDH1A1 (0.61) | ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL6011397 | 0.79 | MEN1 (0.44) | ALDH1A1KMT2AGPR119MEN1SMN1; SMN2 | |
| SCHEMBL25268900 | 0.79 | KMT2A (0.48) | ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL25274092 | 0.78 | GPR119 (0.57) | KMT2AGPR119MEN1 | |
| SCHEMBL8171108 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL28978030 | 0.77 | GPR119 (0.58) | KMT2AGPR119MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4328219-A1 | SOS1 DEGRADING AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-02-28 | — | — | EP | disclosed |