Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | AOC1 | P19801 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27147088 | 0.74 | KDM4C (0.47) | KDM4CAOC1AOC3CYP11B1CYP11B2 | |
| SCHEMBL143257 | 0.69 | NAMPT (0.32) | KDM4CHIF1AKDM4E | |
| SCHEMBL28674191 | 0.67 | MEN1 (0.44) | ALDH1A1GAA | |
| SCHEMBL23671318 | 0.67 | NQO1 (0.35) | KDM4E | |
| SCHEMBL9413722 | 0.67 | KDM4C (0.46) | KDM4CKDM4EGAASIRT3TDP1 | |
| SCHEMBL4754435 | 0.66 | AOC1 (0.57) | KDM4CAOC1AOC3KDM4ECA12 | |
| SCHEMBL30448578 | 0.66 | AOC1 (0.57) | KDM4CAOC1AOC3KDM4ECA12 | |
| SCHEMBL3569822 | 0.66 | SIRT3 (0.61) | KDM4CAOC1AOC3MAP2K3MAPK14 | |
| SCHEMBL17723987 | 0.65 | KDM4C (0.71) | KDM4CAOC1AOC3MAP2K3MAPK14 | |
| SCHEMBL28674177 | 0.62 | FAAH (0.48) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044098-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |