SCHEMBL4754435

SCHEMBL4754435

CNc1ccncc1NC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC1 P19801 6/20 0.57
AOC3 Q16853 6/20 0.57
KDM4C Q9H3R0 1/20 0.55
CHUK O15111 1/20 0.42
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
PTGS1 P23219 3/20 0.38
PTGS2 P35354 3/20 0.38
TP53 P04637 2/20 0.37
CYP3A4 P08684 2/20 0.37
MAPT P10636 2/20 0.37
CASP1 P29466 2/20 0.37
BLM P54132 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
CASP7 P55210 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30448578 1.00 AOC1 (0.57) AOC1AOC3KDM4CCHUKCA12
SCHEMBL827896 0.80
SCHEMBL1630931 0.80
SCHEMBL3953493 0.80 PTGS1 (0.59) AOC1AOC3KDM4CPTGS1PTGS2
SCHEMBL23460857 0.78
SCHEMBL9998811 0.78
SCHEMBL10141340 0.78
SCHEMBL10141341 0.78
SCHEMBL18986531 0.78
SCHEMBL2046959 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954709-A Preparation method of sulfoxide compound, aniline compound and preparation method of aniline compound 帕潘纳(北京)科技有限公司 2025-05-09 CN claimed
CN-117942277-B Skin anti-wrinkle and repairing composition and preparation method thereof 广州联颖化妆品有限公司 2025-01-24 CN claimed
CN-118320125-A Supermolecule self-assembled nano diagnosis and treatment agent based on fluorinated cyclodextrin and porphyrin, and preparation method and application thereof 中山大学 2024-07-12 CN claimed
CN-117756996-A Rust-resistant polycarboxylate superplasticizer for ultra-high-performance concrete and preparation method thereof 中交二航武汉港湾新材料有限公司 2024-03-26 CN claimed
CN-116693590-A Fusidic acid derivative and preparation method and application thereof 南京工业大学 2023-09-05 CN claimed
CN-115322126-B Polyaromatic hydrocarbon compound and preparation method and application thereof 九江学院 2023-04-28 CN claimed
CN-115960115-A Fluorescein derivative and preparation method and application thereof 石河子大学 2023-04-14 CN claimed
CN-115322126-A Polyaromatic hydrocarbon compound and preparation method and application thereof 九江学院 2022-11-11 CN claimed
CN-113248831-A Efficient PP flame-retardant master batch and preparation method thereof 苏州羽凡工程塑料有限公司 2021-08-13 CN claimed
US-11046663-B2 Entecavir intermediate, synthetic method thereof and synthetic method for entecavir LAUNCH-PHARMA TECHNOLOGIES, LTD. (CN) 2021-06-29 US claimed
CN-111039945-B Purification method for protecting meropenem 山东安弘制药有限公司 2021-04-20 CN claimed
CN-109705063-B Entecavir intermediate and synthetic method thereof, and synthetic method of entecavir 广州市朗启医药科技有限责任公司 2021-01-01 CN claimed
CN-111825738-A Betulin derivative and hydrophilic modification product thereof, nano solution and preparation method thereof 中检科医药科技(北京)集团有限公司 2020-10-27 CN claimed
CN-109503337-B Triptycene oxygen-containing straight-chain diol functional material, preparation and application thereof 北京理工大学 2020-09-25 CN claimed
US-20200255390-A1 ENTECAVIR INTERMEDIATE, SYNTHETIC METHOD THEREOF AND SYNTHETIC METHOD FOR ENTECAVIR LAUNCH-PHARMA TECHNOLOGIES, LTD. (CN) 2020-08-13 US claimed
CN-111039945-A Purification method for protecting meropenem 山东安弘制药有限公司 2020-04-21 CN claimed
CN-109705063-A The synthetic method of entecavir midbodies and its synthetic method and Entecavir 广州市朗启医药科技有限责任公司 2019-05-03 CN claimed
CN-105504293-B A kind of preparation and application of fluorescence star block copolymer 北京化工大学 2019-03-01 CN claimed
CN-102311454-B Compound lipid containing porphyrin ring functional groups, preparation method and application thereof HARBIN INST OF TECHNOLOGY 2014-06-04 CN claimed
CN-122055058-A Biaryl compound and method for controlling plant disease 住友化学株式会社 2026-05-15 CN disclosed
CN-119954709-A Preparation method of sulfoxide compound, aniline compound and preparation method of aniline compound 帕潘纳(北京)科技有限公司 2025-05-09 CN disclosed
US-12260969-B2 Conductive film, method for producing same, conductor, resist pattern formation method, and laminate MITSUBISHI CHEMICAL CORPORATION (JP) 2025-03-25 US disclosed
CN-116693590-B Fusidic acid derivative and preparation method and application thereof 南京工业大学 2025-03-18 CN disclosed
CN-119139560-A Injectable hydrogel with anti-inflammatory and drainage functions and capable of promoting anal fistula to heal and preparation method thereof 中山大学附属第五医院 2024-12-17 CN disclosed
US-20240301264-A1 Thermally Conductive Electrically Resistive Low Density Adhesive ZEPHYROS, INC. 2024-09-12 US disclosed
CN-118320125-A Supermolecule self-assembled nano diagnosis and treatment agent based on fluorinated cyclodextrin and porphyrin, and preparation method and application thereof 中山大学 2024-07-12 CN disclosed
CN-118164952-A Preparation method of masmipide 山东新时代药业有限公司 2024-06-11 CN disclosed
CN-115262031-B Fluorescent chitin nanofiber and preparation method and application thereof 南京林业大学 2024-04-02 CN disclosed
CN-117756996-A Rust-resistant polycarboxylate superplasticizer for ultra-high-performance concrete and preparation method thereof 中交二航武汉港湾新材料有限公司 2024-03-26 CN disclosed
CN-117402200-A Perylene derivative and preparation method and application thereof 西北师范大学 2024-01-16 CN disclosed
EP-4264731-A1 THERMALLY CONDUCTIVE ELECTRICALLY RESISTIVE LOW DENSITY ADHESIVE Zephyros Inc. (US) 2023-10-25 EP disclosed
CN-116848703-A Heat conductive resistive low density adhesive 泽费罗斯股份有限公司 2023-10-03 CN disclosed
CN-116693590-A Fusidic acid derivative and preparation method and application thereof 南京工业大学 2023-09-05 CN disclosed
CN-115960115-A Fluorescein derivative and preparation method and application thereof 石河子大学 2023-04-14 CN disclosed
CN-111825738-B Betulin derivative and hydrophilic modification product thereof, nano solution and preparation method thereof 中检科医药科技(北京)集团有限公司 2023-03-14 CN disclosed
CN-112881680-B Method for preparing dsDNA-linked magnetic particles 深圳市卓润生物科技有限公司 2022-11-15 CN disclosed
CN-115262031-A Fluorescent chitin nano-fiber and preparation method and application thereof 南京林业大学 2022-11-01 CN disclosed
CN-113123124-B High-temperature-resistant carbon fiber sizing agent containing alkylated graphene, and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-10-14 CN disclosed
CN-114933582-A Based on pair H 2 O 2 Responsive tea extract EGCG prodrug and preparation method and application thereof 江苏下蜀黄土农业科技有限公司 2022-08-23 CN disclosed
WO-2022129299-A1 THERMALLY CONDUCTIVE ELECTRICALLY RESISTIVE LOW DENSITY ADHESIVE ZEPHYROS, INC. (US) 2022-06-23 WO disclosed
CN-111819637-B Conductive film and method for producing same, conductive body, method for forming resist pattern, and laminate 三菱化学株式会社 2022-05-31 CN disclosed
US-20220151985-A1 IMMUNOSTIMULATOR AND FOOD OR BEVERAGE FOR IMMUNOSTIMULATION Amino Up Co., Ltd. (JP) 2022-05-19 US disclosed
EP-3950066-A1 IMMUNOSTIMULATOR AND FOOD OR BEVERAGE FOR IMMUNOSTIMULATION Amino Up Co., Ltd. (JP) 2022-02-09 EP disclosed
CN-113710325-A Immunostimulant and food and drink for immunostimulation 阿明诺株式会社 2021-11-26 CN disclosed
CN-113248831-A Efficient PP flame-retardant master batch and preparation method thereof 苏州羽凡工程塑料有限公司 2021-08-13 CN disclosed
US-11046663-B2 Entecavir intermediate, synthetic method thereof and synthetic method for entecavir LAUNCH-PHARMA TECHNOLOGIES, LTD. (CN) 2021-06-29 US disclosed
CN-112881680-A Method for preparing dsDNA-linked magnetic particles 深圳市卓润生物科技有限公司 2021-06-01 CN disclosed
CN-111039945-B Purification method for protecting meropenem 山东安弘制药有限公司 2021-04-20 CN disclosed
EP-3144351-B1 CONDUCTIVE COMPOSITION, ANTISTATIC FILM, LAMINATE AND PRODUCTION THEREFOR, AND PRODUCTION METHOD FOR PHOTOMASK MITSUBISHI CHEM CORP (JP) 2021-03-31 EP disclosed
EP-3767639-A1 CONDUCTIVE FILM, METHOD FOR PRODUCING SAME, CONDUCTOR, RESIST PATTERN FORMATION METHOD, AND LAMINATE Mitsubishi Chemical Corporation (JP) 2021-01-20 EP disclosed
US-20210005343-A1 CONDUCTIVE FILM, METHOD FOR PRODUCING SAME, CONDUCTOR, RESIST PATTERN FORMATION METHOD, AND LAMINATE MITSUBISHI CHEMICAL CORPORATION (JP) 2021-01-07 US disclosed
CN-109705063-B Entecavir intermediate and synthetic method thereof, and synthetic method of entecavir 广州市朗启医药科技有限责任公司 2021-01-01 CN disclosed
CN-112028583-A Anti-permeability wear-resistant concrete and preparation method thereof 浙江拓邦混凝土有限公司 2020-12-04 CN disclosed
CN-106661335-B Conductive composition, antistatic film, laminate, method for producing same, and method for producing photomask 三菱化学株式会社 2020-11-27 CN disclosed
CN-111825738-A Betulin derivative and hydrophilic modification product thereof, nano solution and preparation method thereof 中检科医药科技(北京)集团有限公司 2020-10-27 CN disclosed
CN-111819637-A Conductive film and method for producing same, conductive body, method for forming resist pattern, and laminate 三菱化学株式会社 2020-10-23 CN disclosed
WO-2020203593-A1 IMMUNOSTIMULATOR AND FOOD OR BEVERAGE FOR IMMUNOSTIMULATION 株式会社アミノアップ 2020-10-08 WO disclosed
US-20200255390-A1 ENTECAVIR INTERMEDIATE, SYNTHETIC METHOD THEREOF AND SYNTHETIC METHOD FOR ENTECAVIR LAUNCH-PHARMA TECHNOLOGIES, LTD. (CN) 2020-08-13 US disclosed
CN-111039945-A Purification method for protecting meropenem 山东安弘制药有限公司 2020-04-21 CN disclosed
CN-107337748-B A kind of styrene copolymer and preparation method thereof with reversible crosslink key 四川大学 2019-11-26 CN disclosed
CN-108251104-B A kind of substituted indole -2- carboxylic acids Bcl-2 small-molecule fluorescent probe and its application 山东大学 2019-11-05 CN disclosed
WO-2019177096-A1 CONDUCTIVE FILM, METHOD FOR PRODUCING SAME, CONDUCTOR, RESIST PATTERN FORMATION METHOD, AND LAMINATE 三菱ケミカル株式会社 2019-09-19 WO disclosed
CN-107628999-B The preparation method of Aripiprazole dodecylate 苏州华健瑞达医药技术有限公司 2019-07-02 CN disclosed
CN-106680257-B β -galactosidase fluorescence sensor based on silicon nanowires and preparation method and application thereof 中国科学院理化技术研究所 2019-05-14 CN disclosed
CN-109705063-A The synthetic method of entecavir midbodies and its synthetic method and Entecavir 广州市朗启医药科技有限责任公司 2019-05-03 CN disclosed
CN-105504293-B A kind of preparation and application of fluorescence star block copolymer 北京化工大学 2019-03-01 CN disclosed
CN-108251104-A A kind of substituted indole -2- carboxylic acids Bcl-2 small-molecule fluorescent probes and its application 山东大学 2018-07-06 CN disclosed
US-20170261854-A1 CONDUCTIVE COMPOSITION, ANTISTATIC FILM, LAMINATE AND PRODUCTION THEREFOR, AND PRODUCTION METHOD FOR PHOTOMASK MITSUBISHI CHEMICAL CORPORATION (JP) 2017-09-14 US disclosed
US-20170137468-A1 MODULATION OF COMPLEMENT ACTIVITY UCB HOLDINGS, INC. 2017-05-18 US disclosed
EP-3144351-A1 CONDUCTIVE COMPOSITION, ANTISTATIC FILM, LAMINATE AND PRODUCTION THEREFOR, AND PRODUCTION METHOD FOR PHOTOMASK Mitsubishi Rayon Co., Ltd. (JP) 2017-03-22 EP disclosed
CN-105968523-A Nano reinforcing antioxidant geogrid and preparation method thereof 安徽杰奥玛克合成材料科技有限公司 2016-09-28 CN disclosed
EP-2474551-B1 Organic semiconductor compound, and transistor and electronic device including the same SAMSUNG ELECTRONICS CO LTD (KR) 2014-01-01 EP disclosed
US-7872059-B2 Polyurethanes, acryl resins, and metal (cobalt, nickel, palladium, and/or ruthenium); engravable flexographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-01-18 US disclosed
US-7872059-B2 Polyurethanes, acryl resins, and metal (cobalt, nickel, palladium, and/or ruthenium); engravable flexographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-01-18 US disclosed
US-20100266539-A1 CHEMOKINE RECEPTOR ANTAGONIST AND MEDICAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2010-10-21 US disclosed
US-7732442-B2 Chemokine receptor antagonist and medical use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2010-06-08 US disclosed
WO-2008154023-A1 NOVEL USES OF PPAR DELTA AGONISTS CERENIS THERAPEUTICS S.A. (FR) 2008-12-18 WO disclosed
WO-2008136815-A2 5, 6-RING ANNULATED INDOLE DERIVATIVES AND USE THEREOF SCHERING CORPORATION (US) 2008-11-13 WO disclosed
US-20080194762-A1 Polyurethanes, acryl resins, and metal (cobalt, nickel, palladium, and/or ruthenium); engravable flexographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20070254886-A1 Chemokine Receptor Antagonist and Medical Use Thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2007-11-01 US disclosed
CN-1744903-A Process for the preparation of 2' -branched nucleosides IDENIX CAYMAN LTD (KY) 2006-03-08 CN disclosed
US-6867281-B2 Highly conducting and transparent thin films formed from new fluorinated derivatives of 3,4-ethylenedioxythiophene THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2005-03-15 US disclosed
WO-2005020293-A2 HIGHLY CONDUCTING AND TRANSPARENT THIN FILMS FORMED FROM NEW FLUORINATED DERIVATIVES OF 3,4-ETHYLENEDIOXYTHIOPHENE THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2005-03-03 WO disclosed
US-20040214985-A1 HIGHLY CONDUCTING AND TRANSPARENT THIN FILMS FORMED FROM NEW FLUORINATED DERIVATIVES OF 3,4-ETHYLENEDIOXYTHIOPHENE THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2004-10-28 US disclosed
EP-0753002-A1 MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS AMGEN INC. (US) 1997-01-15 EP disclosed
WO-1995026972-A1 MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS AMGEN INC. (US) 1995-10-12 WO disclosed
WO-1993011132-A1 METHOD OF PREPARING THE ANTIBIOTIC CEFACLOR CIBA-GEIGY AG (CH) 1993-06-10 WO disclosed
US-5166435-A Hydrogenation with platinum catalyst of nitro compound in presence of nitrogen base and organophosphorus compound AKZO N.V. (NL) 1992-11-24 US disclosed
EP-0192003-B1 PREPARATION OF 4-SUBSTITUTED PYRIDINES AND QUATERNARY PYRIDINE SALTS USEFUL THEREFOR NEPERA, INC. (US) 1989-08-02 EP disclosed
US-4772713-A Quaternary pyridine salts useful for preparation of 4-substituted pyridines NEPERA, INC. (US) 1988-09-20 US disclosed
US-4672121-A ACRYLAMIDE QUATERNIZING AGENTS, NUCLEOPHILIC DISPLACEMENT AT PARA POSITION, DEQUATERNIZATION NEPERA CHEMICAL CO. (US) 1987-06-09 US disclosed
US-4672121-A ACRYLAMIDE QUATERNIZING AGENTS, NUCLEOPHILIC DISPLACEMENT AT PARA POSITION, DEQUATERNIZATION NEPERA CHEMICAL CO. (US) 1987-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170137468-A1 MODULATION OF COMPLEMENT ACTIVITY C5, C3AR1, CFH AOC1 521/4885AOC3 650/4885KDM4C 3479/4885
US-20200255390-A1 ENTECAVIR INTERMEDIATE, SYNTHETIC METHOD THEREOF AND SYNTHETIC METHOD FOR ENTECAVIR ENTPD5, SAMHD1, ENTPD8 AOC1 3256/4885AOC3 4185/4885KDM4C 3726/4885
US-20220151985-A1 IMMUNOSTIMULATOR AND FOOD OR BEVERAGE FOR IMMUNOSTIMULATION IFNG, IL2, NFATC1 AOC1 1081/4885AOC3 3519/4885KDM4C 3495/4885
US-20100266539-A1 CHEMOKINE RECEPTOR ANTAGONIST AND MEDICAL USE THEREOF CCR5, CCR4, CCR1 AOC1 2456/4885AOC3 2814/4885KDM4C 4511/4885
US-11046663-B2 Entecavir intermediate, synthetic method thereof and synthetic method for entecavir ENTPD5, SAMHD1, ENTPD8 AOC1 3256/4885AOC3 4185/4885KDM4C 3726/4885
US-20070254886-A1 Chemokine Receptor Antagonist and Medical Use Thereof CCR5, CCR4, CCR1 AOC1 2456/4885AOC3 2814/4885KDM4C 4511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.