SCHEMBL2714531

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18266813	0.92	JAK2 (0.46)	ROS1ALKROCK2ROCK1NR3C1
	SCHEMBL2713526	0.90	ROS1 (0.52)	ROS1ALKROCK2ROCK1NR3C1
	SCHEMBL2715796	0.89	HDAC1 (0.42)	ROS1ALKNR3C1JAK2JAK1
	SCHEMBL2713652	0.89	NR3C2 (0.53)	ROS1ALKJAK2JAK1TYK2
	SCHEMBL2716720	0.87	SCN9A (0.57)	ROS1ALKROCK2ROCK1NR3C1
	SCHEMBL2714956	0.86	ROCK2 (0.51)	ROS1ALKROCK2ROCK1
	SCHEMBL2716810	0.83	SCN3A (0.55)	ROS1ALKROCK2SCN3AJAK2
	SCHEMBL18266707	0.83	JAK2 (0.40)	ROS1ALKJAK2JAK1TYK2
	SCHEMBL18266811	0.83	JAK2 (0.40)	ROS1ALKJAK2JAK1TYK2
	SCHEMBL2718299	0.82	MLYCD (0.52)	ROS1SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.