Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 7/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15786506 | 1.00 | HTR2A (0.44) | HTR2AGABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL24681122 | 0.89 | HTR2A (0.47) | HTR2AGABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL28830508 | 0.85 | HTR2A (0.34) | HTR2ACYP1A2ALOX5MEN1KMT2A | |
| SCHEMBL28830511 | 0.85 | HTR2A (0.34) | HTR2ACYP1A2ALOX5MEN1KMT2A | |
| SCHEMBL17532645 | 0.81 | NR1I2 (0.41) | HTR2ALMNACYP1A2ALOX5MAPT | |
| SCHEMBL11079558 | 0.80 | HTR2A (0.58) | HTR2AGABBR2GABBR1LMNACYP2C9 | |
| Hydrochloric Acid SCHEMBL1866896 | 0.78 | HTR2A (0.56) | HTR2AGABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL3838209 | 0.76 | IGF1R (0.39) | HTR2ACYP1A2ALOX5MEN1KMT2A | |
| SCHEMBL16070602 | 0.76 | IGF1R (0.39) | HTR2ACYP1A2ALOX5MEN1KMT2A | |
| SCHEMBL1046532 | 0.73 | ALOX5 (0.41) | HTR2ALMNACYP1A2ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044657-A1 | BIOCATALYSTS AND METHODS THEREOF | TESARO, INC. (US) | 2024-02-29 | — | — | WO | disclosed |