Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 5/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.45 |
| ▸ | SDCBP | O00560 | 1/20 | 0.43 |
| ▸ | SDC2 | P34741 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27147147 | 1.00 | PIN1 (0.46) | PIN1HPGDSACKR3SDCBPSDC2 | |
| SCHEMBL30807227 | 0.91 | HDAC1 (0.42) | HPGDSACKR3HDAC1HDAC6HDAC3 | |
| SCHEMBL30807363 | 0.87 | HDAC1 (0.43) | PIN1HPGDSACKR3SDCBPSDC2 | |
| SCHEMBL25359464 | 0.87 | TDP1 (0.48) | PIN1HPGDSACKR3HDAC1HDAC6 | |
| SCHEMBL25359468 | 0.87 | TDP1 (0.48) | PIN1HPGDSACKR3HDAC1HDAC6 | |
| SCHEMBL30807346 | 0.86 | PIN1 (0.45) | PIN1HPGDSHDAC1HDAC6HDAC8 | |
| SCHEMBL27107144 | 0.83 | HDAC1 (0.43) | HPGDSACKR3SDCBPSDC2HDAC1 | |
| SCHEMBL7097142 | 0.83 | ALDH1A1 (0.54) | HPGDSACKR3SDCBPSDC2HDAC1 | |
| SCHEMBL27154325 | 0.82 | HDAC1 (0.39) | HPGDSACKR3SDCBPSDC2HDAC1 | |
| SCHEMBL27154326 | 0.82 | HDAC1 (0.39) | HPGDSACKR3SDCBPSDC2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044744-A2 | PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2024-02-29 | — | — | WO | disclosed |