SCHEMBL7097142

SCHEMBL7097142

CC(C)(C)OC(=O)NCc1ccc(-c2nc(C(=O)O)cs2)cc1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
PPARA Q07869 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
HPGDS O60760 1/20 0.46
HDAC1 Q13547 5/20 0.45
HDAC6 Q9UBN7 4/20 0.45
HDAC3 O15379 3/20 0.45
PTPN1 P18031 1/20 0.45
ACKR3 P25106 1/20 0.45
GRM2 Q14416 1/20 0.45
NAMPT P43490 1/20 0.43
SDCBP O00560 1/20 0.43
SDC2 P34741 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6392541 0.89 HPGDS (0.47) PPARAL3MBTL1HPGDSHDAC1HDAC6
SCHEMBL27144466 0.87 CYP3A4 (0.56) ALDH1A1HDAC1HDAC6HDAC3ACKR3
SCHEMBL27107073 0.86 RAB9A (0.56) ALDH1A1PPARAL3MBTL1HPGDSHDAC1
SCHEMBL27147147 0.83 PIN1 (0.46) PPARAHPGDSHDAC1HDAC6HDAC3
SCHEMBL27147149 0.83 PIN1 (0.46) PPARAHPGDSHDAC1HDAC6HDAC3
SCHEMBL2025129 0.83 ALDH1A1 (0.57) ALDH1A1L3MBTL1HPGDS
SCHEMBL29879564 0.82 PPARA (0.45) ALDH1A1PPARAL3MBTL1HDAC1HDAC6
SCHEMBL27107144 0.82 HDAC1 (0.43) PPARAL3MBTL1HPGDSHDAC1HDAC6
SCHEMBL3595386 0.81 ACHE (0.51) ALDH1A1HPGDSHDAC1HDAC6HDAC3
SCHEMBL30807227 0.81 HDAC1 (0.42) PPARAL3MBTL1HPGDSHDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062407-A1 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER UNIV WAKE FOREST HEALTH SCIENCES (US) 2026-03-05 US disclosed
US-20250381278-A1 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER UNIV WAKE FOREST HEALTH SCIENCES (US) 2025-12-18 US disclosed
EP-4577211-A2 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER Wake Forest University Health Sciences (US) 2025-07-02 EP disclosed
US-20250011316-A1 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER WAKE FOREST UNIVERSITY HEALTH SCIENCES 2025-01-09 US disclosed
WO-2024044744-A2 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2024-02-29 WO disclosed
WO-2003090680-A2 NOVEL PHENYL DERIVATIVES AS INDUCERS OF APOPTOSIS AXYS PHARMACEUTICALS, INC. (US) 2003-11-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062407-A1 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER PRDX1, PRDX3, PRDX2 ALDH1A1 748/4885PPARA 357/4885L3MBTL1 3333/4885
US-20250011316-A1 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER PRDX1, PRDX2, PRDX6 ALDH1A1 331/4885PPARA 1815/4885L3MBTL1 4526/4885
US-20250381278-A1 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER PRDX1, PRDX2, PRDX6 ALDH1A1 319/4885PPARA 1762/4885L3MBTL1 4648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.