Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | UGCG | Q16739 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.32 |
| ▸ | MGLL | Q99685 | 3/20 | 0.31 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPC | P11150 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27147404 | 0.80 | FAAH (0.37) | ABHD6CRHR1MCHR1MGLLHDAC4 | |
| SCHEMBL30012519 | 0.80 | FAAH (0.37) | ABHD6CRHR1MCHR1MGLLHDAC4 | |
| SCHEMBL27246517 | 0.74 | FFAR4 (0.34) | ABHD6MGLLPROKR1 | |
| SCHEMBL30013207 | 0.70 | MGLL (0.49) | ABHD6MGLLHDAC4 | |
| SCHEMBL27150619 | 0.70 | MGLL (0.49) | ABHD6MGLLHDAC4 | |
| SCHEMBL27151949 | 0.70 | MGLL (0.40) | ABHD6MGLLHDAC4 | |
| SCHEMBL30012659 | 0.70 | MGLL (0.40) | ABHD6MGLLHDAC4 | |
| SCHEMBL27246520 | 0.69 | MGLL (0.51) | PDK2CYP3A4MCHR1MGLLPROKR1 | |
| SCHEMBL30013143 | 0.68 | ABHD6 (0.43) | ABHD6MGLLHDAC4 | |
| SCHEMBL27153173 | 0.68 | ABHD6 (0.43) | ABHD6MGLLHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4326714-A1 | HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-02-28 | — | — | EP | claimed |
| EP-4326714-A1 | HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-02-28 | — | — | EP | disclosed |