SCHEMBL2714760

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2715892	0.92	TSHR (0.38)	TSHRADORA3ADORA2AADORA2BADORA1
	SCHEMBL2716402	0.90	CDK12 (0.38)	TSHRGSK3AGSK3BPTGESMAPK8
	SCHEMBL2717211	0.89	GSK3B (0.38)	TSHRKLKB1CHRM4GSK3AGSK3B
	SCHEMBL16234576	0.88	SCN9A (0.40)	TSHRKLKB1CHRM4GSK3AGSK3B
	SCHEMBL2713691	0.84	PTGES (0.45)	TSHRKLKB1PTGESSCN9A
	SCHEMBL2714447	0.84	SCN9A (0.44)	KLKB1ADORA3ADORA2AADORA1CHRM4
	SCHEMBL2715879	0.82	CNR2 (0.36)	TSHRGSK3AGSK3BPTGESMMP13
	SCHEMBL2716857	0.82	RIPK1 (0.40)	MAPK1CNR2
	SCHEMBL2716818	0.81	GSK3B (0.38)	TSHRGSK3AGSK3BMMP13CNR2
	SCHEMBL27931740	0.81	MMP13 (0.48)	KLKB1CHRM4MMP13CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.