Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | TERT | O14746 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034694 | 1.00 | LMNA (0.46) | LMNAHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL20960104 | 1.00 | LMNA (0.46) | LMNAHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL20960130 | 1.00 | LMNA (0.46) | LMNAHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL27142984 | 1.00 | LMNA (0.46) | LMNAHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL23754414 | 0.91 | LMNA (0.42) | LMNAHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL23754413 | 0.91 | LMNA (0.42) | LMNAHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL8993611 | 0.91 | ALDH1A1 (0.41) | LMNAHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL31528936 | 0.89 | LMNA (0.50) | LMNAHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL25341107 | 0.89 | LMNA (0.50) | LMNAHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL19662286 | 0.89 | LMNA (0.50) | LMNAHSD17B10KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250249123-A1 | LIPIDS AND COMPOSITIONS THEREOF | GENERATION BIO CO. | 2025-08-07 | — | — | US | disclosed |
| US-12263228-B2 | Lipids and compositions thereof | GENERATION BIO CO. (US) | 2025-04-01 | — | — | US | disclosed |
| US-20240285796-A1 | CATIONIC LIPIDS AND COMPOSITIONS THEREOF | GENERATION BIO CO. | 2024-08-29 | — | — | US | disclosed |
| US-20240226325-A1 | CATIONIC LIPIDS AND COMPOSITIONS THEREOF | GENERATION BIO CO. | 2024-07-11 | — | — | US | disclosed |
| EP-4326235-A2 | CATIONIC LIPIDS AND COMPOSITIONS THEREOF | Generation Bio Co. (US) | 2024-02-28 | — | — | EP | disclosed |
| CN-117545469-A | Cationic lipids and compositions thereof | 世代生物公司 | 2024-02-09 | — | — | CN | disclosed |
| WO-2022226008-A2 | CATIONIC LIPIDS AND COMPOSITIONS THEREOF | GENERATION BIO CO. (US) | 2022-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226325-A1 | CATIONIC LIPIDS AND COMPOSITIONS THEREOF | C1R, LRBA, LIPG | LMNA 26/4885HSD17B10 1464/4885KMT2A 1137/4885 |
| US-12263228-B2 | Lipids and compositions thereof | C1R, LIPG, LRBA | LMNA 49/4885HSD17B10 1313/4885KMT2A 1064/4885 |
| US-20250249123-A1 | LIPIDS AND COMPOSITIONS THEREOF | C1R, LIPG, LRBA | LMNA 49/4885HSD17B10 1313/4885KMT2A 1064/4885 |
| US-20240285796-A1 | CATIONIC LIPIDS AND COMPOSITIONS THEREOF | C1R, LRBA, LIPG | LMNA 32/4885HSD17B10 1525/4885KMT2A 1156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.