Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.34 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27150846 | 0.86 | ATM (0.42) | L3MBTL1MRGPRX4KDM4EALDH1A1ALPL | |
| SCHEMBL21078799 | 0.82 | L3MBTL1 (0.42) | HCAR2L3MBTL1MRGPRX4CYP2C9CYP2C19 | |
| SCHEMBL15350265 | 0.79 | L3MBTL1 (0.42) | HCAR2L3MBTL1MRGPRX4CYP2C9CYP2C19 | |
| SCHEMBL2715676 | 0.78 | L3MBTL1 (0.54) | HCAR2L3MBTL1MRGPRX4CYP2C9CYP2C19 | |
| SCHEMBL3430654 | 0.76 | HCAR2 (0.44) | HCAR2L3MBTL1CYP2C9CYP2C19P4HA1 | |
| SCHEMBL15350077 | 0.75 | L3MBTL1 (0.41) | HCAR2L3MBTL1CYP2C9CYP2C19KDM4E | |
| SCHEMBL27149274 | 0.75 | AAK1 (0.38) | — | |
| SCHEMBL15350967 | 0.74 | SCN9A (0.40) | HCAR2L3MBTL1MRGPRX4CYP2C9CYP2C19 | |
| SCHEMBL21078902 | 0.74 | AAK1 (0.39) | HCAR2L3MBTL1CYP2C9CYP2C19KDM4E | |
| SCHEMBL21078750 | 0.73 | L3MBTL1 (0.40) | HCAR2L3MBTL1MRGPRX4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4326714-A1 | HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-02-28 | — | — | EP | disclosed |
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |